Introduction：Basic information about CAS 4684-32-6|Picrinine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Picrinine |
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| CAS Number | 4684-32-6 | Molecular Weight | 338.400 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 501.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H22N2O3 | Melting Point | / |
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| MSDS | / | Flash Point | 256.9±30.1 °C |
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Names
| Name | Picrinin |
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| Synonym | More Synonyms |
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Picrinine BiologicalActivity
| Description | Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>5-Lipoxygenase |
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| Target | 5-Lipoxygenase |
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| References | [1]. Smith JM, et, al. Total synthesis of the akuammiline alkaloid picrinine. J Am Chem Soc. 2014 Mar 26;136(12):4504-7. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 501.1±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H22N2O3 |
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| Molecular Weight | 338.400 |
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| Flash Point | 256.9±30.1 °C |
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| Exact Mass | 338.163055 |
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| PSA | 50.80000 |
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| LogP | 2.49 |
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| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
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| Index of Refraction | 1.677 |
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| InChIKey | BDXYPHKGNUGUFG-WAYFEFRKSA-N |
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| SMILES | CC=C1CN2C3CC45c6ccccc6NC4(O3)C2CC1C5C(=O)OC |
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Safety Information
Synonyms
| 2H,12H-6,12a-Epoxy-2,7a-methanoindolo[2,3-a]quinolizine-14-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-, methyl ester, (2R,3E,6S,7aR,12aR,12bS,14R)- |
| deacetyl-deformopicraline |
| desacetyldesformopicraline |
| Methyl (2α,5α,19E)-1,2-dihydro-2,5-epoxyakuammilan-17-oate |
| Picrinine |
| vincaridine |
| 2Alpha,5Alpha-Epoxy-1,2-dihydroakuammilan-17-oic acid methyl ester |
