CAS 62758-13-8|Resazurin sodium salt
Introduction：Basic information about CAS 62758-13-8|Resazurin sodium salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Resazurin sodium salt | ||
|---|---|---|---|
| CAS Number | 62758-13-8 | Molecular Weight | 251.170 |
| Density | / | Boiling Point | 477.2ºC at 760 mmHg |
| Molecular Formula | C12H6NNaO4 | Melting Point | >200ºC |
| MSDS | ChineseUSA | Flash Point | 242.4ºC |
Names
| Name | Resazurin sodium salt |
|---|---|
| Synonym | More Synonyms |
Resazurin sodium salt BiologicalActivity
| Description | Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersBiochemical Assay ReagentsResearch Areas >>Others |
| In Vitro | Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. No viable bacteria are detected 24 h post-inoculation following inclusion of Resazurin sodium salt in TSBc cultures of F. tularensis LVS at the concentration of 44 μM. Lowering the Resazurin sodium salt concentration to as little as 4.4 μM still results in a 10-fold reduction in viable F. tularensis LVS compare to growth medium alone. Both Resazurin sodium salt treatments result in a significant decrease in viable F. tularensis LVS bacteria over 22 h. Treatment with Resazurin sodium salt significantly reduces the number of viable F. tularensis LVS bacteria in HEK293 cells 22 h post-infection[1]. |
| Cell Assay | F. tularensis is cultured in TSBc supplemented with 44 μM Resazurin sodium salt at 37°C with shaking for 24 h. At select time points, a Spectronic 200 Spectrophotometer is used to measure the absorbance at 600 nm and 570 nm to detect the presence of Resazurin sodium salt and resorufin, respectively. The ratio of these two optical densities is used to evaluate reduction of Resazurin sodium salt to resorufin over time[1]. |
| References | [1]. Schmitt DM, et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis. Front Cell Infect Microbiol. 2013 Dec 6;3:93. |
Chemical & Physical Properties
| Boiling Point | 477.2ºC at 760 mmHg |
|---|---|
| Melting Point | >200ºC |
| Molecular Formula | C12H6NNaO4 |
| Molecular Weight | 251.170 |
| Flash Point | 242.4ºC |
| Exact Mass | 251.019455 |
| PSA | 78.73000 |
| LogP | 2.47010 |
| InChIKey | IVGPGQSSDLDOLH-UHFFFAOYSA-M |
| SMILES | O=c1ccc2[n+]([O-])c3ccc([O-])cc3oc-2c1.[Na+] |
| Storage condition | Store at RT. |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Water Solubility | soluble |
Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R36/37/38 |
| Safety Phrases | S26-S36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2934999090 |
Customs
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide, sodium salt (1:1) |
| 7-hydroxy-10-oxy-phenoxazin-3-one,sodium-compound |
| ResazurinGr |
| EINECS 263-718-5 |
| 7-sodiooxy-3H-phenoxazin-3-one 10-oxide |
| DIAZORESORCINOL |
| RESAZURIN SODIUM |
| 7-hydroxy-3H-phenoxazin-3-one 10-oxide sodium salt |
| Sodium 3-oxo-3H-phenoxazin-7-olate 10-oxide |
| Resazurine |
| RESAZOIN |
| REZAZURIN |
| RESAZURIN NA-SALT |
| SODIUM RESAZURIN |
| REISHIMUSHROOM.P.E |
| 7-Hydroxy-10-oxy-phenoxazin-3-on,Natrium-Verbindung |
| MFCD00005036 |
