CAS 1034-01-1|Octyl gallate
| Common Name | Octyl gallate | ||
|---|---|---|---|
| CAS Number | 1034-01-1 | Molecular Weight | 282.33 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 482.9±40.0 °C at 760 mmHg |
| Molecular Formula | C15H22O5 | Melting Point | 101-104 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 177.1±20.8 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | octyl gallate |
|---|---|
| Synonym | More Synonyms |
Octyl gallate BiologicalActivity
| Description | Octyl gallate (Progallin O) is widely used as a food additive, with antimicrobial and antioxidant activity[1][2]. Octyl gallate (Progallin O) shows selective and sensitive fluorescent property[2]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| In Vitro | Octyl gallate has antimicrobial activity over H. pylori, with a minimum inhibitory concentration (MIC) value of 125 µg/mL[1]. |
| References | [1]. Wolf VG, et al. Octyl gallate, a food additive with potential beneficial properties to treat Helicobacter pylori infection. Food Funct. 2017 Jul 19;8(7):2500-2511. [2]. Wang Q, et al. Octyl gallate: An antioxidant demonstrating selective and sensitive fluorescent property. Food Chem. 2017 Mar 15;219:268-273. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 482.9±40.0 °C at 760 mmHg |
| Melting Point | 101-104 °C(lit.) |
| Molecular Formula | C15H22O5 |
| Molecular Weight | 282.33 |
| Flash Point | 177.1±20.8 °C |
| Exact Mass | 282.146729 |
| PSA | 86.99000 |
| LogP | 5.26 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.552 |
| InChIKey | NRPKURNSADTHLJ-UHFFFAOYSA-N |
| SMILES | CCCCCCCCOC(=O)c1cc(O)c(O)c(O)c1 |
| Storage condition | 0-6°C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1960 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 53A,183,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 60 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FAONAU FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. Volume(issue)/page/year: 38A,22,1965
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H317 |
| Precautionary Statements | P280-P301 + P312 + P330 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R43 |
| Safety Phrases | S24-S37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 1 |
| RTECS | LW8225000 |
| HS Code | 2918290000 |
Customs
| HS Code | 2918290000 |
|---|---|
| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |
Articles28
More Articles| Kinetics of the transformation of n-propyl gallate and structural analogs in the perfused rat liver. Toxicol. Appl. Pharmacol. 273(1) , 35-46, (2013) n-Propyl gallate and its analogs are used in foods and other products to prevent oxidation. In the liver the compound exerts several harmful effects, especially gluconeogenesis inhibition. The mode of... | |
| Antioxidants modulate molecular mobility, oxygen permeability, and microstructure in zein films. J. Agric. Food Chem. 59(24) , 13173-80, (2011) The effect of octyl gallate and propyl gallate on the molecular mobility, oxygen permeability, and microstructure of zein/glycerol films was studied. Films were cast from 70% ethanol/water containing ... | |
| Occurrence and environmental stress responses of two plastid terminal oxidases in Haematococcus pluvialis (Chlorophyceae). Planta 230(1) , 191-203, (2009) The plastid terminal oxidase (PTOX) is a plastoquinol oxidase involved in carotenoid biosynthesis in higher plants, and may also represent the elusive oxidase in chlororespiration. Haematococcus pluvi... |
Synonyms
| Gallic Acid n-Octyl Ester |
| Octyl gallate |
| MFCD00002197 |
| n-octyl gallate |
| Octyl 3,4,5-trihydroxybenzoate |
| Benzoic acid, 3,4,5-trihydroxy-, octyl ester |
| 3,4,5-Trihydroxy benzoic acid octyl ester |
| EINECS 213-853-0 |
