Introduction：Basic information about CAS 23778-52-1|Pentaethylene glycol monomethyl ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pentaethylene glycol monomethyl ether |
|---|
| CAS Number | 23778-52-1 | Molecular Weight | 252.305 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 332.3±32.0 °C at 760 mmHg |
|---|
| Molecular Formula | C11H24O6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 154.7±25.1 °C |
|---|
Names
| Name | 2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol |
|---|
| Synonym | More Synonyms |
|---|
Pentaethylene glycol monomethyl ether BiologicalActivity
| Description | Pentaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 332.3±32.0 °C at 760 mmHg |
|---|
| Molecular Formula | C11H24O6 |
|---|
| Molecular Weight | 252.305 |
|---|
| Flash Point | 154.7±25.1 °C |
|---|
| Exact Mass | 252.157288 |
|---|
| PSA | 66.38000 |
|---|
| LogP | -2.23 |
|---|
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
|---|
| Index of Refraction | 1.441 |
|---|
| InChIKey | SLNYBUIEAMRFSZ-UHFFFAOYSA-N |
|---|
| SMILES | COCCOCCOCCOCCOCCO |
|---|
Safety Information
| Hazard Codes | Xi |
|---|
| Risk Phrases | 36/37/38 |
|---|
| Safety Phrases | 26-36/37/39 |
|---|
| HS Code | 2909499000 |
|---|
Customs
| HS Code | 2909499000 |
|---|
| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
|---|
Synonyms
| 2-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethanol |
| 2,5,8,11,14-Pentaoxahexadecan-16-ol |
| 1PG |
| 3,6,9,12,15-pentaoxahexadecanol |
| PENTAETHYLENE GLYCOL MONOMETHYL ETHER |
| 3,6,9,12,15-Pentaoxahexadecan-1-ol |
| 14-methoxy-3,6,9,12-tetraoxa-tetradecan-1-ol |
