CAS 5636-92-0|Picloxydine
Introduction：Basic information about CAS 5636-92-0|Picloxydine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Picloxydine | ||
|---|---|---|---|
| CAS Number | 5636-92-0 | Molecular Weight | 475.37800 |
| Density | 1.5g/cm3 | Boiling Point | 703.8ºC at 760 mmHg |
| Molecular Formula | C20H24Cl2N10 | Melting Point | / |
| MSDS | / | Flash Point | 379.5ºC |
Names
| Name | picloxydine |
|---|
Picloxydine BiologicalActivity
| Description | Picloxydine is a heterocyclic biguanide with antibacterial and antiplaque activity. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
| Target | Bacterial[1] |
| In Vivo | 0.4% Picloxydine produces a highly significant drop in the number of aerobic organisms. 0.4% Picloxydine is far more effective than 0.2% Picloxydine or chlorhexidine in reducing the total viable count of oral aerobic and anaerobic organisms[1]. Picloxydine is also used in eye drops in the topical therapy of trachoma[2]. |
| References | [1]. Newcomb GM, et al. An in vivo comparison of chlorhexidine and picloxydine mouthrinses: a possible association between chemical structure and antiplaque activity. J Periodontol. 1977 May;48(5):282-4. [2]. Obikili AG, et al. A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma. Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 1988;65(3-4):119-32. |
Chemical & Physical Properties
| Density | 1.5g/cm3 |
|---|---|
| Boiling Point | 703.8ºC at 760 mmHg |
| Molecular Formula | C20H24Cl2N10 |
| Molecular Weight | 475.37800 |
| Flash Point | 379.5ºC |
| Exact Mass | 474.15600 |
| PSA | 150.00000 |
| LogP | 4.25580 |
| Index of Refraction | 1.717 |
| InChIKey | YNCLPFSAZFGQCD-UHFFFAOYSA-N |
| SMILES | NC(=Nc1ccc(Cl)cc1)N=C(N)N1CCN(C(N)=NC(N)=Nc2ccc(Cl)cc2)CC1 |
| Storage condition | 2-8℃ |
