CAS 93-39-0|Skimmin

Introduction:Basic information about CAS 93-39-0|Skimmin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSkimmin
CAS Number93-39-0Molecular Weight324.28
Density1.6±0.1 g/cm3Boiling Point632.0±55.0 °C at 760 mmHg
Molecular FormulaC15H16O8Melting Point221-222ºC
MSDSChineseUSAFlash Point239.3±25.0 °C

Names

Name7-hydroxycoumarin glucoside
SynonymMore Synonyms

Skimmin BiologicalActivity

DescriptionSkimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity[1].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Zhang S, et al. Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition. Evid Based Complement Alternat Med. 2013;2013:819296.

Chemical & Physical Properties

Density1.6±0.1 g/cm3
Boiling Point632.0±55.0 °C at 760 mmHg
Melting Point221-222ºC
Molecular FormulaC15H16O8
Molecular Weight324.28
Flash Point239.3±25.0 °C
Exact Mass324.084503
PSA129.59000
LogP-1.50
Vapour Pressure0.0±1.9 mmHg at 25°C
Index of Refraction1.661
InChIKeyVPAOSFFTKWUGAD-TVKJYDDYSA-N
SMILESO=c1ccc2ccc(OC3OC(CO)C(O)C(O)C3O)cc2o1

Safety Information

Hazard CodesXi
RIDADRNONH for all modes of transport

Articles2

More Articles
Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition.

Evid. Based. Complement. Alternat. Med. 2013 , 819296, (2013)

Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent. In the current st...

Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats.

Eur. J. Pharmacol. 692(1-3) , 78-83, (2012)

Skimmin, a major active ingredient from Hydrangea paniculata, was considered to have the possible preventive effect on the progression of diabetic nephropathy based on the traditional Chinese medicine...

Synonyms

2H-1-Benzopyran-2-one, 7- (β-D-glucopyranosyloxy)-
7-(Glucosyloxy)coumarin
Skimmin
7-Hydroxycoumarin-7-glucoside
Skimmine
UMBELLIFERONE GLUCOSIDE
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-
Coumarin, 7-(β-D-glucopyranosyloxy)-
2-Oxo-2H-chromen-7-yl β-D-glucopyranoside
HYDROXYCOUMARIN-GLUCOSIDE,7
Skimmin (8CI)
7-(b-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one
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