Introduction:Basic information about CAS 93-39-0|Skimmin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Skimmin |
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| CAS Number | 93-39-0 | Molecular Weight | 324.28 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 632.0±55.0 °C at 760 mmHg |
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| Molecular Formula | C15H16O8 | Melting Point | 221-222ºC |
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| MSDS | ChineseUSA | Flash Point | 239.3±25.0 °C |
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Names
| Name | 7-hydroxycoumarin glucoside |
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| Synonym | More Synonyms |
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Skimmin BiologicalActivity
| Description | Skimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Zhang S, et al. Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition. Evid Based Complement Alternat Med. 2013;2013:819296. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 632.0±55.0 °C at 760 mmHg |
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| Melting Point | 221-222ºC |
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| Molecular Formula | C15H16O8 |
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| Molecular Weight | 324.28 |
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| Flash Point | 239.3±25.0 °C |
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| Exact Mass | 324.084503 |
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| PSA | 129.59000 |
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| LogP | -1.50 |
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| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
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| Index of Refraction | 1.661 |
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| InChIKey | VPAOSFFTKWUGAD-TVKJYDDYSA-N |
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| SMILES | O=c1ccc2ccc(OC3OC(CO)C(O)C(O)C3O)cc2o1 |
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Safety Information
| Hazard Codes | Xi |
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| RIDADR | NONH for all modes of transport |
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Articles2
More Articles
| Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition. Evid. Based. Complement. Alternat. Med. 2013 , 819296, (2013) Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent. In the current st... | |
| Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats. Eur. J. Pharmacol. 692(1-3) , 78-83, (2012) Skimmin, a major active ingredient from Hydrangea paniculata, was considered to have the possible preventive effect on the progression of diabetic nephropathy based on the traditional Chinese medicine... | |
Synonyms
| 2H-1-Benzopyran-2-one, 7- (β-D-glucopyranosyloxy)- |
| 7-(Glucosyloxy)coumarin |
| Skimmin |
| 7-Hydroxycoumarin-7-glucoside |
| Skimmine |
| UMBELLIFERONE GLUCOSIDE |
| 2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)- |
| Coumarin, 7-(β-D-glucopyranosyloxy)- |
| 2-Oxo-2H-chromen-7-yl β-D-glucopyranoside |
| HYDROXYCOUMARIN-GLUCOSIDE,7 |
| Skimmin (8CI) |
| 7-(b-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one |