CAS 2848-96-6|7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate

Introduction:Basic information about CAS 2848-96-6|7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name7-chloro-5-(2-chlorophenyl)-1,3-dihydro-2-oxo-2H-1,4-benzodiazepin-3-yl acetate
CAS Number2848-96-6Molecular Weight363.19500
Density1.45 g/cm3Boiling Point524.4ºC at 760 mmHg
Molecular FormulaC17H12Cl2N2O3Melting Point/
MSDS/Flash Point270.9ºC
Symbol
GHS07, GHS09
Signal WordWarning

Names

Name[7-chloro-5-(2-chlorophenyl)-2-oxo-1,3-dihydro-1,4-benzodiazepin-3-yl] acetate
SynonymMore Synonyms

Chemical & Physical Properties

Density1.45 g/cm3
Boiling Point524.4ºC at 760 mmHg
Molecular FormulaC17H12Cl2N2O3
Molecular Weight363.19500
Flash Point270.9ºC
Exact Mass362.02200
PSA67.76000
LogP3.24570
Vapour Pressure4.33E-11mmHg at 25°C
Index of Refraction1.656
InChIKeyCYDZMDOLVUBPNL-UHFFFAOYSA-N
SMILESCC(=O)OC1N=C(c2ccccc2Cl)c2cc(Cl)ccc2NC1=O

Safety Information

Symbol
GHS07, GHS09
Signal WordWarning
Hazard StatementsH302-H410
Precautionary StatementsP273-P501
RIDADRUN 3077 9 / PGIII

Articles7

More Articles
Stereoselective binding of 3-acetoxy-, and 3-hydroxy-1,4-benzodiazepine-2-ones to human serum albumin. Selective allosteric interaction with warfarin enantiomers.

Biochem. Pharmacol. 35(2) , 263-9, (1986)

Stereoselective binding of oxazepam, lorazepam, temazepam and methyl lorazepam as well as of their acetates to human serum albumin was investigated by different techniques. The 2'-chlorine and the N(1...

Stereoselective kinetics of warfarin binding to human serum albumin: effect of an allosteric interaction.

Chirality 14(5) , 442-8, (2002)

Kinetic and equilibrium binding studies were performed on the interaction of warfarin enantiomers with human serum albumin (HSA) in the absence and presence of lorazepam acetate (LoAc) enantiomers. Bi...

Stereoselective allosteric binding interaction on human serum albumin between ibuprofen and lorazepam acetate.

Chirality 11(2) , 115-20, (1999)

The effect of ibuprofen enantiomers on the stereoselective binding of 3-acyloxy-1,4-benzodiazepines to human serum albumin (HSA) was studied using both native and Sepharose-immobilized protein. (S)-Lo...

Synonyms

lorazepam acetate
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