Introduction：Basic information about CAS 3772-76-7|Sulfamethomidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sulfamethomidine |
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| CAS Number | 3772-76-7 | Molecular Weight | 294.33000 |
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| Density | 1.418g/cm3 | Boiling Point | 501.6ºC at 760mmHg |
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| Molecular Formula | C12H14N4O3S | Melting Point | / |
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| MSDS | / | Flash Point | 257.2ºC |
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Names
| Name | 4-amino-N-(6-methoxy-2-methylpyrimidin-4-yl)benzenesulfonamide |
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| Synonym | More Synonyms |
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Sulfamethomidine BiologicalActivity
| Description | Sulfamethomidine is an antibacterial agent[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. TRUANT JP, et al. ENHANCEMENT OF INHIBITORY EFFECT AGAINST GRAM-NEGATIVE ORGANISMS WITH COLISTIN SULFATE AND CERTAIN SULFONAMIDES. Antimicrob Agents Chemother (Bethesda). 1963;161:420-426. |
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Chemical & Physical Properties
| Density | 1.418g/cm3 |
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| Boiling Point | 501.6ºC at 760mmHg |
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| Molecular Formula | C12H14N4O3S |
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| Molecular Weight | 294.33000 |
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| Flash Point | 257.2ºC |
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| Exact Mass | 294.07900 |
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| PSA | 115.58000 |
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| LogP | 2.91160 |
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| Index of Refraction | 1.633 |
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| InChIKey | QKLSCPPJEVXONT-UHFFFAOYSA-N |
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| SMILES | COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(C)n1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- WP0110000
- CHEMICAL NAME :
- Sulfanilamide, N(sup 1)-(6-methoxy-2-methyl-4-pyrimidinyl)-
- CAS REGISTRY NUMBER :
- 3772-76-7
- BEILSTEIN REFERENCE NO. :
- 0284949
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C12-H14-N4-O3-S
- MOLECULAR WEIGHT :
- 294.36
- WISWESSER LINE NOTATION :
- T6N CNJ B1 DO1 FMSWR DZ
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3 gm/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- REFERENCE :
- SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,17,1973
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 6 gm/kg
- SEX/DURATION :
- female 9-14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- REFERENCE :
- SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,7,1973
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 3 gm/kg
- SEX/DURATION :
- female 7-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)
- REFERENCE :
- SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,17,1973
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Safety Information
Customs
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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Synonyms
| Methofazine |
| N1-<6-Methoxy-2-methyl-pyrimidinyl-(4)>-sulfanilamid |
| 4-amino-N-(6-methoxy-2-methyl-pyrimidin-4-yl)-benzenesulfonamide |
| Duroprocin |
| Sulfametomidina [INN-Spanish] |
| Sulfamethomidine |
| Sulfametomidine |
| Methofadin |
| Sulfanilsaeure-(6-methoxy-2-methyl-pyrimidin-4-ylamid) |
| sulfanilic acid-(6-methoxy-2-methyl-pyrimidin-4-ylamide) |
| SA 412 |
| EINECS 223-219-5 |
| Sulfametomidinum [INN-Latin] |
| Solfametomidina [DCIT] |
| 4-<4-Amino-benzolsulfonylamino>-6-methoxy-2-methyl-pyrimidin |
| Sulfamethomidin |
