CAS 41933-33-9|2-Benzyl-4,5-dichloropyridazine-3(2H)-one

Introduction：Basic information about CAS 41933-33-9|2-Benzyl-4,5-dichloropyridazine-3(2H)-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	2-Benzyl-4,5-dichloropyridazine-3(2H)-one
CAS Number	41933-33-9	Molecular Weight	255.10000
Density	1.38g/cm3	Boiling Point	338ºC at 760 mmHg
Molecular Formula	C₁₁H₈Cl₂N₂O	Melting Point	87ºC
MSDS	/	Flash Point	158.2ºC

Names

Name	2-Benzyl-4,5-dichloropyridazin-3(2H)-one
Synonym	More Synonyms

BiologicalActivity

Description	EcDsbB-IN-9 (Compound 9) is a potent E. coli DsbB (EcDsbB) inhibitor with an IC50 of 1.7 μM and a Ki of 46 nM[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Others >>Others
Target	IC50: 1.7 μM (EcDsbB)[1] Ki: 46 nM (EcDsbB)[1]
In Vitro	EcDsbB-IN-9 (Compound 9) (0-100 μM) causes accumulation of reduced DsbA (EcDsbB substrate) and inhibits oxidation of DsbA with an IC50 of 8.5 ± 0.6 μM[1].

Chemical & Physical Properties

Density	1.38g/cm3
Boiling Point	338ºC at 760 mmHg
Melting Point	87ºC
Molecular Formula	C₁₁H₈Cl₂N₂O
Molecular Weight	255.10000
Flash Point	158.2ºC
Exact Mass	254.00100
PSA	34.89000
LogP	2.59840
Index of Refraction	1.626
InChIKey	AJHBQZQCDCTOFD-UHFFFAOYSA-N
SMILES	O=c1c(Cl)c(Cl)cnn1Cc1ccccc1

Safety Information

Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
HS Code	2933990090

Customs

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

2-benzyl-4,5-dichloropyridazin-3-one

Recommended......