CAS 7698-93-3|beta-Estradiol 17-hemisuccinate
| Common Name | beta-Estradiol 17-hemisuccinate | ||
|---|---|---|---|
| CAS Number | 7698-93-3 | Molecular Weight | 372.455 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 570.1±50.0 °C at 760 mmHg |
| Molecular Formula | C22H28O5 | Melting Point | 162-164°C (lit.) |
| MSDS | ChineseUSA | Flash Point | 198.7±23.6 °C |
| Symbol | GHS07, GHS08 | Signal Word | Warning |
Names
| Name | 4-[[(8R,9S,13S,14S,17S)-3-hydroxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]oxy]-4-oxobutanoic acid |
|---|---|
| Synonym | More Synonyms |
beta-Estradiol 17-hemisuccinate BiologicalActivity
| Description | β-Estradiol 17-hemisuccinate is a synthetic derivative of estradiol (HY-B0141)[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Gaikwad NW. Ultra performance liquid chromatography-tandem mass spectrometry method for profiling of steroid metabolome in human tissue. Anal Chem. 2013 May 21;85(10):4951-60. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 570.1±50.0 °C at 760 mmHg |
| Melting Point | 162-164°C (lit.) |
| Molecular Formula | C22H28O5 |
| Molecular Weight | 372.455 |
| Flash Point | 198.7±23.6 °C |
| Exact Mass | 372.193665 |
| PSA | 83.83000 |
| LogP | 4.64 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.598 |
| InChIKey | YJPIDPAGJSWWBE-FNIAAEIWSA-N |
| SMILES | CC12CCC3c4ccc(O)cc4CCC3C1CCC2OC(=O)CCC(=O)O |
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H332-H351 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn |
| Risk Phrases | 20/21/22-40 |
| Safety Phrases | 22-36 |
| RIDADR | NONH for all modes of transport |
Articles15
More Articles| Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats. J. Neuroimmunol. , (2008) Estrogen has been shown to attenuate the inflammatory response following injury or lipopolysaccharide treatment in several organ systems. Estrogen's actions are transduced through two estrogen recepto... | |
| Steroid-bovine serum albumin conjugates: molecular characterization and their interaction with androgen and estrogen receptors. J. Steroid Biochem. 24(5) , 1017-31, (1986) Conjugates of testosterone-3-carboxymethyloxime (T-3-CMO), testosterone-17-hemisuccinate (T-17-HS), 17 beta-estradiol-6-carboxymethyloxime (E-6-CMO), or 17 beta-estradiol-17-hemisuccinate (E-17-HS) an... | |
| Prevention of bridge binding in immunoassays: a general estradiol tracer structure. J. Steroid Biochem. 32(2) , 251-7, (1989) Iodinated estradiol tracers were synthesized with three different bridges connecting the radiolabelled moiety to the steroid core: Hemisuccinate, carboxymethyloxime and amide. Taking these iodinated t... |
Synonyms
| 17beta-Estradiol hemisuccinate |
| 1,3,5(10)-Estratriene-3,17beta-diol 17-hemisuccinate |
| 4-{[(14beta,17alpha)-3-Hydroxyestra-1,3,5(10)-Trien-17-Yl]oxy}-4-Oxobutanoic Acid |
| Eutocol (TN) |
| 4-{[(17β)-3-Hydroxyestra-1,3,5(10)-trien-17-yl]oxy}-4-oxobutanoic acid |
| 17BETA-ESTRADIOL 17-HEMISUCCINATE |
| Estradiol-17-hemisuccinate |
| Butanedioic acid, mono[(17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl] ester |
| beta-Estradiol 17-hemisuccinate |
