CAS 52248-03-0|S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt
Introduction：Basic information about CAS 52248-03-0|S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt | ||
|---|---|---|---|
| CAS Number | 52248-03-0 | Molecular Weight | 570.639 |
| Density | / | Boiling Point | / |
| Molecular Formula | C22H30N6O8S2 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | 5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxy-Adenosine tosylate |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>CancerResearch Areas >>Inflammation/ImmunologyResearch Areas >>Neurological Disease |
| Target | Human Endogenous Metabolite |
| References | [1]. G M Bressa. et al. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. [2]. Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6. [3]. Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42. |
Chemical & Physical Properties
| Molecular Formula | C22H30N6O8S2 |
|---|---|
| Molecular Weight | 570.639 |
| Exact Mass | 570.156677 |
| PSA | 273.51000 |
| LogP | 1.33920 |
| InChIKey | VHPOFDUCFKOUHV-XKGORWRGSA-N |
| SMILES | C[S+](CCC(N)C(=O)O)CC1OC(n2cnc3c(N)ncnc32)C(O)C1O.Cc1ccc(S(=O)(=O)[O-])cc1 |
Synonyms
| [(3S)-3-Amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl}methylsulfonium 4-methylbenzenesulfonate |
| SAM p-toluenesulfonate salt |
| Methionine,S-adenosyl-,DL |
| S-Adenosyl-DL-methionine |
| S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt |
| [(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium,4-methylbenzenesulfonate |
| S-Adenosyl methionione |
| methyl-S-adenosyl-L-Met |
| S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt |
| AdoMet SAM p-toluenesulfonate salt |
