CAS 2441-41-0|PALGLY

Introduction:Basic information about CAS 2441-41-0|PALGLY, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePALGLY
CAS Number2441-41-0Molecular Weight313.48
Density1.0±0.1 g/cm3Boiling Point491.8±28.0 °C at 760 mmHg
Molecular FormulaC18H35NO3Melting Point/
MSDSUSAFlash Point251.2±24.0 °C

Names

Name2-(hexadecanoylamino)acetic acid
SynonymMore Synonyms

PALGLY BiologicalActivity

DescriptionPalmitoylglycine, a novel endogenous lipid, acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Palmitoylglycine induces transient influx of calcium followed by nitric oxide production via calcium-sensitive nitric-oxide synthase enzymes. Palmitoylglycine potently inhibits heat-evoked firing of nociceptive neurons in rat dorsal horn[1].
Related CatalogSignaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelSignaling Pathways >>Immunology/Inflammation >>NO SynthaseResearch Areas >>Neurological Disease
References

[1]. Neta Rimmerman, et al. N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons. Mol Pharmacol. 2008 Jul;74(1):213-24.

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point491.8±28.0 °C at 760 mmHg
Molecular FormulaC18H35NO3
Molecular Weight313.48
Flash Point251.2±24.0 °C
Exact Mass313.261688
PSA66.40000
LogP6.03
Appearance of Characterswhite to off-white
Vapour Pressure0.0±2.7 mmHg at 25°C
Index of Refraction1.468
InChIKeyKVTFEOAKFFQCCX-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCCCCC(=O)NCC(=O)O
Storage condition2-8°C
Water SolubilityDMSO: >10mg/mL

Safety Information

Personal Protective EquipmentEyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
RIDADRNONH for all modes of transport
HS Code2924199090

Customs

HS Code2924199090
Summary2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Synonyms

N-Ethanoyl-Hexadecanamide
PALGLY
N-hexadecanoyl glycine
Palmitoylglycine
QV1MV15
N-palmitatoylglycyne
N-(1-Oxohexadecyl)glycine
N-Hexadecanoylglycine
Glycine, N-(1-oxohexadecyl)-
Hexadecanoylaminoacetic acid N-palmitoyl glycine
Hexadecanoylaminoacetic acid,N-palmitoyl glycine
2-(Hexadecanoylamino)acetic acid
N-palmitoyl glycine
N-Palmitoylglycine
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