CAS 1743-60-8|β-Estradiol 17-acetate

Introduction:Basic information about CAS 1743-60-8|β-Estradiol 17-acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameβ-Estradiol 17-acetate
CAS Number1743-60-8Molecular Weight314.41900
Density1.18g/cm3Boiling Point450.5ºC at 760 mmHg
Molecular FormulaC20H26O3Melting Point/
MSDSChineseUSAFlash Point181.9ºC
Symbol
GHS08
Signal WordDanger

Names

Name17-β-Estradiol 17-acetate
SynonymMore Synonyms

β-Estradiol 17-acetate BiologicalActivity

Descriptionβ-Estradiol 17-acetate is a metabolite of estradiol. Target: Othersβ-Estradiol 17-acetate is a metabolite of estradiol.
Related CatalogSignaling Pathways >>Others >>Estrogen Receptor/ERRResearch Areas >>Endocrinology
References

[1]. http://en.wikipedia.org/wiki/Estradiol

Chemical & Physical Properties

Density1.18g/cm3
Boiling Point450.5ºC at 760 mmHg
Molecular FormulaC20H26O3
Molecular Weight314.41900
Flash Point181.9ºC
Exact Mass314.18800
PSA46.53000
LogP4.18000
Vapour Pressure9.88E-09mmHg at 25°C
Index of Refraction1.583
InChIKeyQAHOQNJVHDHYRN-SLHNCBLASA-N
SMILESCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C

Safety Information

Symbol
GHS08
Signal WordDanger
Hazard StatementsH360
Precautionary StatementsP201-P308 + P313
Personal Protective EquipmentEyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard CodesT: Toxic;
Risk PhrasesR60;R61
Safety PhrasesS53-S45
RIDADRNONH for all modes of transport
WGK Germany3

Articles7

More Articles
Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats.

J. Neuroimmunol. , (2008)

Estrogen has been shown to attenuate the inflammatory response following injury or lipopolysaccharide treatment in several organ systems. Estrogen's actions are transduced through two estrogen recepto...

LCAT facilitates transacylation of 17 beta-estradiol in the presence of HDL3 subfraction.

J. Lipid Res. 43(3) , 392-7, (2002)

It has been shown that estrogens need to be metabolized to their hydrophobic estrogen ester derivatives to act as antioxidants in lipoproteins. Data suggest that 17beta-estradiol (E(2)) becomes esteri...

High-performance liquid chromatographic determination of 17beta-estradiol and 17beta-estradiol-3-acetate solubilities and diffusion coefficents in silicone elastromeric intravaginal rings.

J. Chromatogr. B. Biomed. Sci. Appl. 744(1) , 157-63, (2000)

A rapid, sensitive reversed-phase high-performance liquid chromatographic method has been developed for the determination of in vitro release of 17beta-estradiol and its ester prodrug, 17beta-estradio...

Synonyms

Cardene IV
Cardene SR
Beta-Estradiol 17-acetate
Nicardipino
estradiol 17-acetate
nicardipine
Nicardipine LA
Nicardipinum
β-Estradiol 17-acetate
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