CAS 174568-68-4|Tetramethylrhodamine-6-maleimide

Introduction：Basic information about CAS 174568-68-4|Tetramethylrhodamine-6-maleimide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Tetramethylrhodamine-6-maleimide BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Tetramethylrhodamine-6-maleimide
CAS Number	174568-68-4	Molecular Weight	481.49900
Density	/	Boiling Point	/
Molecular Formula	C₂₈H₂₃N₃O₅	Melting Point	/
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS07	Signal Word	Warning

Names

Name	2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-5-(2,5-dioxopyrrol-1-yl)benzoate
Synonym	More Synonyms

Tetramethylrhodamine-6-maleimide BiologicalActivity

Description	Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Geibel S, et al. Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):964-9. [2]. Loo DD, et al. Conformational changes couple Na+ and glucose transport. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7789-94.

Description

Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Geibel S, et al. Conformational dynamics of the Na+/K+-ATPase probed by voltage clamp fluorometry. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):964-9.

[2]. Loo DD, et al. Conformational changes couple Na+ and glucose transport. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7789-94.

Chemical & Physical Properties

Molecular Formula	C₂₈H₂₃N₃O₅
Molecular Weight	481.49900
Exact Mass	481.16400
PSA	97.13000
LogP	3.52400
InChIKey	SHKRXDBVQOSKJN-UHFFFAOYSA-N
SMILES	CN(C)c1ccc2c(-c3c(C(=O)[O-])cccc3N3C(=O)C=CC3=O)c3ccc(=[N+](C)C)cc-3oc2c1

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
Risk Phrases	R22
Safety Phrases	S36
RIDADR	NONH for all modes of transport

Synonyms

Tetramethylrhodamine-6-maleimide

MFCD01311092

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