CAS 93952-20-6|p,p'-DDD-d8
Introduction：Basic information about CAS 93952-20-6|p,p'-DDD-d8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | p,p'-DDD-d8 | ||
|---|---|---|---|
| CAS Number | 93952-20-6 | Molecular Weight | 328.09000 |
| Density | / | Boiling Point | / |
| Molecular Formula | C14H2Cl4D8 | Melting Point | / |
| MSDS | / | Flash Point | / |
Names
| Name | 4,4′-Dichlorobenzophenone D8 |
|---|
p,p'-DDD-d8 BiologicalActivity
| Description | p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD is a major metabolite of p,p'-DDT. p,p'-DDD occurs in the feces and livers of rats, that are given p,p'-DDT by stomach tube, but not of rats injected intraperitoneally with p,p'-DDT[2][3]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Mendel JL, et al. Conversion of p,p' -DDT to p,p' -DDD by intestinal flora of the rat. Science. 1966;151(3717):1527-1528. [3]. Gerić M, et al. Cytogenetic status of human lymphocytes after exposure to low concentrations of p,p'-DDT, and its metabolites (p,p'-DDE, and p,p'-DDD) in vitro. Chemosphere. 201287(11):1288-1294. |
Chemical & Physical Properties
| Molecular Formula | C14H2Cl4D8 |
|---|---|
| Molecular Weight | 328.09000 |
| Exact Mass | 326.00400 |
| LogP | 5.92900 |
| InChIKey | AHJKRLASYNVKDZ-PGRXLJNUSA-N |
| SMILES | Clc1ccc(C(c2ccc(Cl)cc2)C(Cl)Cl)cc1 |
