Introduction：Basic information about CAS 663921-15-1|NH2-PEG4-CH2CH2COOH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | NH2-PEG4-CH2CH2COOH |
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| CAS Number | 663921-15-1 | Molecular Weight | 265.303 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 409.6±40.0 °C at 760 mmHg |
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| Molecular Formula | C11H23NO6 | Melting Point | / |
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| MSDS | / | Flash Point | 201.5±27.3 °C |
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Names
| Name | 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid |
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| Synonym | More Synonyms |
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NH2-PEG4-CH2CH2COOH BiologicalActivity
| Description | NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Antibody-drug Conjugate >>ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) having enzymatically cleavable groups. WO2018114578A1. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 409.6±40.0 °C at 760 mmHg |
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| Molecular Formula | C11H23NO6 |
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| Molecular Weight | 265.303 |
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| Flash Point | 201.5±27.3 °C |
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| Exact Mass | 265.152527 |
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| PSA | 100.24000 |
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| LogP | -1.92 |
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| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
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| Index of Refraction | 1.469 |
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| InChIKey | DKUZHSDZSMQOGQ-UHFFFAOYSA-N |
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| SMILES | NCCOCCOCCOCCOCCC(=O)O |
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| Storage condition | -20°C |
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Safety Information
Customs
| HS Code | 2922499990 |
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| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| AmbotzPEG1370 |
| Amino-PEG4-acid |
| 15-amino-4,7,10,13-tetraoxapentadecanoic acid |
| 1-Amino-3,6,9,12-tetraoxapentadecan-15-oic acid |
| 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-amino- |
| H2N-PEG4-COOH |
