Introduction:Basic information about CAS 69388-79-0|Sulbactam pivoxil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sulbactam pivoxil |
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| CAS Number | 69388-79-0 | Molecular Weight | 347.384 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 537.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C14H21NO7S | Melting Point | / |
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| MSDS | / | Flash Point | 278.9±30.1 °C |
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Names
| Name | 2,2-dimethylpropanoyloxymethyl 3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
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| Synonym | More Synonyms |
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Sulbactam pivoxil BiologicalActivity
| Description | Sulbactam pivoxil is a prodrug of sulbactam. Sulbactam is a β-lactamase inhibitor which poorly adsorbed from gastrointestinal tract. Sulbactam pivoxil has a better absorption than the parent drug and provides high serum levels after oral administration[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Changov LS, et al. An efficient method for the synthesis of sulbactam pivoxil. Farmaco. 2000;55(2):134-135. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 537.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C14H21NO7S |
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| Molecular Weight | 347.384 |
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| Flash Point | 278.9±30.1 °C |
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| Exact Mass | 347.103882 |
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| PSA | 115.43000 |
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| LogP | -0.02 |
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| Vapour Pressure | 0.0±1.4 mmHg at 25°C |
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| Index of Refraction | 1.538 |
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| InChIKey | OHPVYKXTRACOSQ-ZJUUUORDSA-N |
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| SMILES | CC(C)(C)C(=O)OCOC(=O)C1N2C(=O)CC2S(=O)(=O)C1(C)C |
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Safety Information
Synonyms
| 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S-cis)- |
| Hydroxymethyl (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Pivalate (Ester) 4,4-Dioxide |
| sulbactam pivaloyl-oxymethyl ester |
| (2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 4,4-Dioxide (2,2-Dimethyl-1-oxopropoxy)methyl Ester |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, 4,4-dioxide, (2S,5R)- |
| SULBACTAM PIVOXIL |
| Sulbactam pivoxyl |
| 1,1-dioxopenicillanic acid pivaloyloxymethyl ester |
| [(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| Pivsulbactam |
| Pivoxil sulbactam |