CAS 69388-79-0|Sulbactam pivoxil

Introduction:Basic information about CAS 69388-79-0|Sulbactam pivoxil, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSulbactam pivoxil
CAS Number69388-79-0Molecular Weight347.384
Density1.4±0.1 g/cm3Boiling Point537.5±50.0 °C at 760 mmHg
Molecular FormulaC14H21NO7SMelting Point/
MSDS/Flash Point278.9±30.1 °C

Names

Name2,2-dimethylpropanoyloxymethyl 3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
SynonymMore Synonyms

Sulbactam pivoxil BiologicalActivity

DescriptionSulbactam pivoxil is a prodrug of sulbactam. Sulbactam is a β-lactamase inhibitor which poorly adsorbed from gastrointestinal tract. Sulbactam pivoxil has a better absorption than the parent drug and provides high serum levels after oral administration[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
References

[1]. Changov LS, et al. An efficient method for the synthesis of sulbactam pivoxil. Farmaco. 2000;55(2):134-135.

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point537.5±50.0 °C at 760 mmHg
Molecular FormulaC14H21NO7S
Molecular Weight347.384
Flash Point278.9±30.1 °C
Exact Mass347.103882
PSA115.43000
LogP-0.02
Vapour Pressure0.0±1.4 mmHg at 25°C
Index of Refraction1.538
InChIKeyOHPVYKXTRACOSQ-ZJUUUORDSA-N
SMILESCC(C)(C)C(=O)OCOC(=O)C1N2C(=O)CC2S(=O)(=O)C1(C)C

Safety Information

Hazard CodesXn

Synonyms

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, 4,4-dioxide, (2,2-dimethyl-1-oxopropoxy)methyl ester, (2S-cis)-
Hydroxymethyl (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate Pivalate (Ester) 4,4-Dioxide
sulbactam pivaloyl-oxymethyl ester
(2S-cis)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 4,4-Dioxide (2,2-Dimethyl-1-oxopropoxy)methyl Ester
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, 4,4-dioxide, (2S,5R)-
SULBACTAM PIVOXIL
Sulbactam pivoxyl
1,1-dioxopenicillanic acid pivaloyloxymethyl ester
[(2,2-Dimethylpropanoyl)oxy]methyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide
Pivsulbactam
Pivoxil sulbactam
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