CAS 321-30-2|Adenine hemisulfate
Introduction：Basic information about CAS 321-30-2|Adenine hemisulfate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Adenine hemisulfate | ||
|---|---|---|---|
| CAS Number | 321-30-2 | Molecular Weight | 368.332 |
| Density | / | Boiling Point | 553.5ºC at 760mmHg |
| Molecular Formula | C5H7N5O4S | Melting Point | 285 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 1H-Purin-6-amine sulfate |
|---|---|
| Synonym | More Synonyms |
Adenine hemisulfate BiologicalActivity
| Description | Adenine hemisulfate (6-Aminopurine hemisulfate) is a purine derivative with a variety of roles in biochemistry, including cellular respiration, in the form of both the energy-rich adenosine triphosphate (ATP) and the cofactors nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD), and protein synthesis, as a chemical component of DNA and RNA[1][2]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA Synthesis |
| Target | Human Endogenous Metabolite |
| References | [1]. Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31. [2]. ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27. |
Chemical & Physical Properties
| Boiling Point | 553.5ºC at 760mmHg |
|---|---|
| Melting Point | 285 °C (dec.)(lit.) |
| Molecular Formula | C5H7N5O4S |
| Molecular Weight | 368.332 |
| Exact Mass | 368.076355 |
| PSA | 243.94000 |
| LogP | 1.46060 |
| InChIKey | LQXHSCOPYJCOMD-UHFFFAOYSA-N |
| SMILES | Nc1ncnc2nc[nH]c12.Nc1ncnc2nc[nH]c12.O=S(=O)(O)O |
| Storage condition | Store at RT. |
| Water Solubility | 0.4 g/100 mL |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 232,302,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 47,229,1979 *** REVIEWS *** TOXICOLOGY REVIEW ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,24,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83237 No. of Facilities: 59 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 588 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83237 No. of Facilities: 496 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 5574 (estimated) No. of Female Employees: 2982 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xn |
| Risk Phrases | R22 |
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | AU7140000 |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles3
More Articles| Plantlet regeneration from callus cultures of selected genotype of Aloe vera L.--an ancient plant for modern herbal industries. Appl. Biochem. Biotechnol. 163 , 860-868, (2011) Aloe vera L., a member of Liliaceae, is a medicinal plant and has a number of curative properties. We describe here the development of tissue culture method for high-frequency plantlet regeneration fr... | |
| Rapid in vitro production of cloned plants of Uraria picta (Jacq.) DC-A rare medicinal herb in long-term culture. Appl. Biochem. Biotechnol. 162 , 1929-1937, (2010) An efficient in vitro process for rapid production of cloned plants of Uraria picta has been developed employing nodal stem segments taken from field-grown plants. Explants showed bud-break followed b... | |
| Factors influencing rapid clonal propagation of Chlorophytum arundinaceum (Liliales: Liliaceae), an endangered medicinal plant. Rev. Biol. Trop. 59 , 435-445, (2011) Chlorophytum arundinaceum is an important medicinal plant and its tuberous roots are used for various health ailment treatments. It has become an endangered species in the Eastern Ghats, and a rare me... |
Synonyms
| diadenine sulphate |
| Adenine Sulfate Dihydrate |
| 6-Aminopurine hemisulfate salt |
| 9H-Purin-6-amine sulfate (2:1) |
| EINECS 206-286-5 |
| Bis(6-amino-9H-purin-1-ium) sulfate |
| denine,sulfate |
| Adenine sulfate salt |
| VITAMIN B SULFATE |
| Adenine sulfate |
| 7H-Purin-6-amine, sulfate (2:1) |
| Adenine sulfate,synthetic |
| ADENINE HEMISULFATE |
| MFCD00213655 |
| adeniniumsulfate |
| 9H-purin-6-amine, sulfate (2:1) |
| adenine sulphate |
| 1H-Purin-6-amine sulfate (2:1) |
| Adenine hemisulfate salt |
| Adenine sulfate hydrate |
| 6-Aminopurine hemisulfate salt,Adenine sulfate salt |
| 6-Aminopurine Sulfate Dihydrate |
| 7H-Purin-6-amine sulfate |
| 7H-Purin-6-amine sulfate (2:1) |
| Adenin,Sulfat |
