Introduction:Basic information about CAS 76497-13-7|Sultamicillin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sultamicillin |
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| CAS Number | 76497-13-7 | Molecular Weight | 594.657 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 907.7±65.0 °C at 760 mmHg |
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| Molecular Formula | C25H30N4O9S2 | Melting Point | 190° |
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| MSDS | / | Flash Point | 502.8±34.3 °C |
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Names
| Name | sultamicillin |
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| Synonym | More Synonyms |
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Sultamicillin BiologicalActivity
| Description | Sultamicillin is an orally active double prodrug of Ampicillin/Sulbactan. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with Ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Friedel HA, et al. Sultamicillin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1989 Apr;37(4):491-522. |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 907.7±65.0 °C at 760 mmHg |
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| Melting Point | 190° |
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| Molecular Formula | C25H30N4O9S2 |
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| Molecular Weight | 594.657 |
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| Flash Point | 502.8±34.3 °C |
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| Exact Mass | 594.145447 |
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| PSA | 216.16000 |
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| LogP | -0.29 |
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| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
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| Index of Refraction | 1.668 |
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| InChIKey | OPYGFNJSCUDTBT-PMLPCWDUSA-N |
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| SMILES | CC1(C)SC2C(NC(=O)C(N)c3ccccc3)C(=O)N2C1C(=O)OCOC(=O)C1N2C(=O)CC2S(=O)(=O)C1(C)C |
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| Storage condition | 2-8°C |
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| Water Solubility | Practically insoluble in water, very slightly soluble in methanol, practically insoluble in ethanol (96 per cent). |
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Safety Information
Customs
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 6'-(2-Amino-2-phenylacetamido)penicillanoyloxymethylpenicillanate 1,1-dioxide |
| Sultancillin alkali |
| 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, [[[(2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl]oxy]methyl ester, 4,4-dioxide, (2S,5R)- |
| Unacid PD |
| SultaMcillin Base |
| VD 1827 |
| 1,1-Dioxopenicillanoyloxymethyl 6-(D-a-amino-a-phenylacetamido)penicillanate |
| ({[(2S,5R,6R)-6-{[(2R)-2-Amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl]carbonyl}oxy)methyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
| Sultamicillin |
| Bethadl Orale |
| Sultamicillin Base |
| Baeimex |