Introduction：Basic information about CAS 107-97-1|Sarcosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sarcosine |
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| CAS Number | 107-97-1 | Molecular Weight | 89.093 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 195.1±23.0 °C at 760 mmHg |
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| Molecular Formula | C3H7NO2 | Melting Point | 208-212 °C (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | 71.8±22.6 °C |
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Names
| Name | Sarcosine |
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| Synonym | More Synonyms |
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Sarcosine BiologicalActivity
| Description | Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GlyTSignaling Pathways >>Neuronal Signaling >>GlyTNatural Products >>Acids and AldehydesResearch Areas >>Others |
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| Target | Human Endogenous Metabolite |
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| References | [1]. Zhang HX, et al. The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine. J Physiol. 2009 Jul 1;587(Pt 13):3207-20. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 195.1±23.0 °C at 760 mmHg |
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| Melting Point | 208-212 °C (dec.)(lit.) |
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| Molecular Formula | C3H7NO2 |
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| Molecular Weight | 89.093 |
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| Flash Point | 71.8±22.6 °C |
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| Exact Mass | 89.047676 |
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| PSA | 49.33000 |
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| LogP | -0.79 |
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| Vapour Pressure | 0.2±0.8 mmHg at 25°C |
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| Index of Refraction | 1.431 |
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| Storage condition | Store at RT. |
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| Water Solubility | 1480 g/L (20 ºC) |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- VQ2897000
- CHEMICAL NAME :
- Sarcosine
- CAS REGISTRY NUMBER :
- 107-97-1
- BEILSTEIN REFERENCE NO. :
- 1699442
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C3-H7-N-O2
- MOLECULAR WEIGHT :
- 89.11
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 1 |
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| RTECS | VQ2897000 |
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| HS Code | 29224995 |
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Customs
| HS Code | 2922499990 |
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| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Articles87
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| Long-term application of glycine transporter inhibitors acts antineuropathic and modulates spinal N-methyl-D-aspartate receptor subunit NR-1 expression in rats. Anesthesiology 121(1) , 160-9, (2014) Dysfunction of spinal glycinergic neurotransmission is a major pathogenetic factor in neuropathic pain. The synaptic glycine concentration is controlled by the two glycine transporters (GlyT) 1 and 2.... | |
| Development of High-purity Certified Reference Materials for 17 Proteinogenic Amino Acids by Traceable Titration Methods. Anal. Sci. 31 , 805-14, (2015) To ensure the reliability of amino acid analyses, the National Metrology Institute of Japan of the National Institute of Advanced Industrial Science and Technology (NMIJ/AIST) has developed high-purit... | |
| [Membrane-bound proteases of ompT+ and ompT- Vibrio cholerae strains]. Zh. Mikrobiol. Epidemiol. Immunobiol. (2) , 3-12, (2013) Detection ofproteases in outer membranes (OM) of ompT+ and ompT- Vibrio cholerae strains of O1 and O139 serogroups.Specific sterile preparations of OM were obtained by lysis of live V. cholerae cells ... | |
Synonyms
| Acide (méthylamino)acétique |
| SAR |
| Glycine, N-methyl- |
| sarcosine zwitterion |
| MeNHCH2CO2H |
| MeHNCH2CO2H |
| EINECS 203-538-6 |
| Methylaminoethanoic acid |
| N-methyl-Glycine |
| N-methylaminoacetic acid |
| Sarcosine |
| N-Methylglycocoll |
| N-Methylglycine |
| Methylaminoacetic Acid |
| MFCD00004279 |
| (methylamino)-Acetic acid |
| H-Sar-OH |
