Introduction:Basic information about CAS 81921-35-9|N6-Methyladenosine 5'-Monophosphate Sodium Salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N6-Methyladenosine 5'-Monophosphate Sodium Salt |
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| CAS Number | 81921-35-9 | Molecular Weight | 405.21 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C11H14N5Na2O7P | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | 5'-Adenylic acid, N-methyl-, disodium salt |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a Ka value of 22 µM[1]. N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor[2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| Target | Ki: 22 Glycogen phosphorylase b[1]. Adenylate kinase II[2]. |
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| References | [1]. Groner Y, et al. 5'-Capping structures of Artemia salina mRNA and the translational inhibition by cap analogs. Eur J Biochem. 1976 Dec;71(1):281-93. [2]. Hai TT, et al. Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem. 1982 Oct;25(10):1184-8. |
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Chemical & Physical Properties
| Molecular Formula | C11H14N5Na2O7P |
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| Molecular Weight | 405.21 |
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| Exact Mass | 384.06900 |
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| PSA | 181.89000 |
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| InChIKey | HFOKUKRAZPHTHH-LYYWGVPGSA-L |
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| SMILES | CNc1ncnc2c1ncn2C1OC(COP(=O)([O-])[O-])C(O)C1O.[Na+].[Na+] |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Articles1
More Articles
| AMP analogs: their function in the activation of glycogen phosphorylase b. Eur. J. Biochem. 65 , 553, (1976) A series of AMP analogs has been selected in order to better understand the structural requirements (a) for the efficient binding of the activator molecule at the correct site on phosphorylase b from ... | |
Synonyms
| 00587 N6-METHYLADENOSINE-5'-MONOPHOSPHATE SODIUM SALT |
| N6-Methyladenosine-5'-monophosphate sodium salt |
| N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT |