CAS 81921-35-9|N6-Methyladenosine 5'-Monophosphate Sodium Salt

Introduction:Basic information about CAS 81921-35-9|N6-Methyladenosine 5'-Monophosphate Sodium Salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN6-Methyladenosine 5'-Monophosphate Sodium Salt
CAS Number81921-35-9Molecular Weight405.21
Density/Boiling Point/
Molecular FormulaC11H14N5Na2O7PMelting Point/
MSDSUSAFlash Point/

Names

Name5'-Adenylic acid, N-methyl-, disodium salt
SynonymMore Synonyms

BiologicalActivity

DescriptionN6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a Ka value of 22 µM[1]. N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor[2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
Target

Ki: 22 Glycogen phosphorylase b[1]. Adenylate kinase II[2].

References

[1]. Groner Y, et al. 5'-Capping structures of Artemia salina mRNA and the translational inhibition by cap analogs. Eur J Biochem. 1976 Dec;71(1):281-93.

[2]. Hai TT, et al. Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem. 1982 Oct;25(10):1184-8.

Chemical & Physical Properties

Molecular FormulaC11H14N5Na2O7P
Molecular Weight405.21
Exact Mass384.06900
PSA181.89000
InChIKeyHFOKUKRAZPHTHH-LYYWGVPGSA-L
SMILESCNc1ncnc2c1ncn2C1OC(COP(=O)([O-])[O-])C(O)C1O.[Na+].[Na+]

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Articles1

More Articles
AMP analogs: their function in the activation of glycogen phosphorylase b.

Eur. J. Biochem. 65 , 553, (1976)

A series of AMP analogs has been selected in order to better understand the structural requirements (a) for the efficient binding of the activator molecule at the correct site on phosphorylase b from ...

Synonyms

00587 N6-METHYLADENOSINE-5'-MONOPHOSPHATE SODIUM SALT
N6-Methyladenosine-5'-monophosphate sodium salt
N6-METHYLADENOSINE 5'-MONOPHOSPHATE SODIUM SALT
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