Introduction：Basic information about CAS 521-12-0|Dromostanolone propionate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dromostanolone propionate |
|---|
| CAS Number | 521-12-0 | Molecular Weight | 360.530 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 445.9±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C23H36O3 | Melting Point | 114-120ºC |
|---|
| MSDS | / | Flash Point | 190.5±28.8 °C |
|---|
Names
| Name | dromostanolone propionate |
|---|
| Synonym | More Synonyms |
|---|
Dromostanolone propionate BiologicalActivity
| Description | Dromostanolone propionate (Drostanolone propionate) is a compound has antitumor activity against breast carcinoma[1]. Dromostanolone propionate inhibits the uptake of oestradiol-17ß by the tumour but has no apparent effect on the uptake by normal breast tissue [2]. Dromostanolone propionate implant pellet produces weight gains in animals and suppresses estrus in female animals[3]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
|---|
| References | [1]. Takeuchi S, et al. Clinical experience with dromostanolone propionate (NSC-12198) in breast carcinoma. Saishin Igaku. 1967 May;22(5):1049-54. [2]. N.Deshpande, et al. Accumulation of tritiated oestradiol by human breast tissue. Steroids, 1967 Sep;10(3), 219–232. [3]. Brian H. Vickery . Dromostanolone propionate implant pellet useful for producing weight gains in animals and suppressing estrus in female animals. US3991750A. |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 445.9±45.0 °C at 760 mmHg |
|---|
| Melting Point | 114-120ºC |
|---|
| Molecular Formula | C23H36O3 |
|---|
| Molecular Weight | 360.530 |
|---|
| Flash Point | 190.5±28.8 °C |
|---|
| Exact Mass | 360.266449 |
|---|
| PSA | 43.37000 |
|---|
| LogP | 5.67 |
|---|
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
|---|
| Index of Refraction | 1.522 |
|---|
| InChIKey | NOTIQUSPUUHHEH-UXOVVSIBSA-N |
|---|
| SMILES | CCC(=O)OC1CCC2C3CCC4CC(=O)C(C)CC4(C)C3CCC12C |
|---|
| Storage condition | Controlled Substance, -20?C Freezer |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- BV8067300
- CHEMICAL NAME :
- 5-alpha-Androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-, propionate
- CAS REGISTRY NUMBER :
- 521-12-0
- BEILSTEIN REFERENCE NO. :
- 3161958
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C23-H36-O3
- MOLECULAR WEIGHT :
- 360.59
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,534,1982
|
Safety Information
Synonyms
| Androstan-3-one, 2-methyl-17-(1-oxopropoxy)-, (2α,5α,17β)- |
| 2a-Methyl-17b-(1-oxopropoxy)-5a-androstan-3-one |
| Masteril |
| Dromostanolone 17-propionate |
| MDHT |
| (2α,5α,17β)-2-Methyl-3-oxoandrostan-17-yl propionate |
| Dromostanolone propionate |
| Emdisterone |
| 17β-Hydroxy-2α-methyl-5α-androstan-3-one propionate |
| EINECS 208-303-1 |
| 5α-Androstan-3-one, 17β-hydroxy-2α-methyl-, propionate |
| Drostanolone propionate |
| Masterone |
| (2α,5α,17β)-2-methyl-3-oxoandrostan-17-yl propanoate |
| Permastril |
| Medrotestron propionate |
| 2a-Methylandrostan-17b-ol-3-one Propionate |
| MFCD01669961 |
| Dromostanolone proprionate |
| Drolban |
| Masterid |
| UNII-X20UZ57G4O |
| 17b-Hydroxy-2a-methyl-5a-androstan-3-one propionate |
