Introduction：Basic information about CAS 56632-83-8|2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine |
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| CAS Number | 56632-83-8 | Molecular Weight | 245.21 |
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| Density | 1.8±0.1 g/cm3 | Boiling Point | 500.1±60.0 °C at 760 mmHg |
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| Molecular Formula | C9H12FN3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 256.2±32.9 °C |
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Names
| Name | 4-amino-1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 2’-Deoxy-2’-fluoro-b-D-arabinocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Density | 1.8±0.1 g/cm3 |
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| Boiling Point | 500.1±60.0 °C at 760 mmHg |
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| Molecular Formula | C9H12FN3O4 |
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| Molecular Weight | 245.21 |
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| Flash Point | 256.2±32.9 °C |
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| Exact Mass | 245.081177 |
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| PSA | 110.60000 |
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| LogP | -1.26 |
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| Vapour Pressure | 0.0±2.9 mmHg at 25°C |
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| Index of Refraction | 1.697 |
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| InChIKey | NVZFZMCNALTPBY-PXBUCIJWSA-N |
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| SMILES | Nc1ccn(C2OC(CO)C(O)C2F)c(=O)n1 |
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Synonyms
| 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)- |
| 4-Amino-1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-2(1H)-pyrimidinone |
| 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-cytosine |
| 4-Amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)pyrimidin-2(1H)-one |
| 4-Amino-1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2(1H)-pyrimidinone |
| 2'deoxy-2'-fluoroarabinocytidine |
| 2'-Fluoro-2'-deoxy-arabinofuranosyl-cytidine |
