CAS 89-84-9|2,4-Dihydroxyacetophenone

Introduction：Basic information about CAS 89-84-9|2,4-Dihydroxyacetophenone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2,4-Dihydroxyacetophenone BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles7
8. Synonyms

Common Name	2,4-Dihydroxyacetophenone
CAS Number	89-84-9	Molecular Weight	152.147
Density	1.3±0.1 g/cm3	Boiling Point	319.3±12.0 °C at 760 mmHg
Molecular Formula	C₈H₈O₃	Melting Point	143-144.5 °C(lit.)
MSDS	ChineseUSA	Flash Point	161.1±16.1 °C
Symbol	GHS05, GHS07	Signal Word	Danger

Names

Name	2',4'-dihydroxyacetophenone
Synonym	More Synonyms

2,4-Dihydroxyacetophenone BiologicalActivity

Description	2',4'-Dihydroxyacetophenone (Resacetophenone) is acetophenone carrying hydroxy substituents at positions 2' and 4'. A plant metabolite.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>OthersNatural Products >>Phenols
References	[1]. Li XJ, et al. Bioactive metabolites from biotransformation of paeonol by the white-rot basidiomycete Coriolus versicolor. Nat Prod Commun. 2011 Aug;6(8):1129-30.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	319.3±12.0 °C at 760 mmHg
Melting Point	143-144.5 °C(lit.)
Molecular Formula	C₈H₈O₃
Molecular Weight	152.147
Flash Point	161.1±16.1 °C
Exact Mass	152.047348
PSA	57.53000
LogP	1.74
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.595
InChIKey	SULYEHHGGXARJS-UHFFFAOYSA-N
SMILES	CC(=O)c1ccc(O)cc1O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AM7525000

CHEMICAL NAME :: Acetophenone, 2',4'-dihydroxy-

CAS REGISTRY NUMBER :: 89-84-9

BEILSTEIN REFERENCE NO. :: 1282505

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H8-O3

MOLECULAR WEIGHT :: 152.16

WISWESSER LINE NOTATION :: QR CQ DV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year: 6,1,1967 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2830 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IHFCAY Industrial Hygiene Foundation of America, Chemical and Toxicological Series, Bulletin. (Pittsburgh, PA) 1947-69. Volume(issue)/page/year: 6,1,1967 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 20 mg/kg

SEX/DURATION :: female 4 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina

REFERENCE :: JSICAZ Journal of Scientific and Industrial Research, Section C: Biological Sciences. (New Delhi, India) V.14-21, 1955-62. For publisher information, see IJEBA6. Volume(issue)/page/year: 19,264,1960

Safety Information

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	AM7525000
HS Code	2914391000

Customs

HS Code	2914501900
Summary	2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles7

Bioactive metabolites from biotransformation of paeonol by the white-rot basidiomycete Coriolus versicolor.

Nat. Prod. Commun. 6(8) , 1129-30, (2011)

Biotransformation of paeonol (1) with the white-rot basidiomycete Coriolus versicolor afforded two metabolites, 2,4-dihydroxyacetophenone (2) and 2,5-dihydroxy-4-methoxyacetophenone (3), which were id...

Multifaceted defense against antagonistic microbes in developing offspring of the parasitoid wasp Ampulex compressa (Hymenoptera, Ampulicidae).

PLoS ONE 9(6) , e98784, (2014)

Effective antimicrobial strategies are essential adaptations of insects to protect themselves, their offspring, and their foods from microbial pathogens and decomposers. Larvae of the emerald cockroac...

Synthesis, Characterization and Biological Studies of Metal(II) Complexes of (3E)-3-[(2-{(E)-[1-(2,4-Dihydroxyphenyl) ethylidene]amino}ethyl)imino]-1-phenylbutan-1-one Schiff Base.

Molecules 20 , 9788-802, (2015)

Co(II), Ni(II), Zn(II) and Cu(II) complexes of (3E)-3-[(2-{(E)-[1-(2,4-dihydroxyphenyl)ethylidene]amino}ethyl)imino]-1-phenylbutan-1-one (DEPH2) derived from ethylenediamine, 2',4'-dihydroxyacetopheno...

Synonyms

2,4-Dihydroxyacetophenone

1-(2,4-Dihydroxyphenyl)ethanone

Ethanone, 1-(2,4-dihydroxyphenyl)-

EINECS 201-945-3

2',4'-Dihydroxyacetophenone

MFCD00002279

Acetophenone, 2',4'-dihydroxy-

Resacetophenone

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