CAS 371-40-4|4-Fluoroaniline
Introduction：Basic information about CAS 371-40-4|4-Fluoroaniline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Fluoroaniline | ||
|---|---|---|---|
| CAS Number | 371-40-4 | Molecular Weight | 111.117 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 188.9±13.0 °C at 760 mmHg |
| Molecular Formula | C6H6FN | Melting Point | -1.9 °C |
| MSDS | ChineseUSA | Flash Point | 73.9±0.0 °C |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | 4-fluoroaniline |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 188.9±13.0 °C at 760 mmHg |
| Melting Point | -1.9 °C |
| Molecular Formula | C6H6FN |
| Molecular Weight | 111.117 |
| Flash Point | 73.9±0.0 °C |
| Exact Mass | 111.048424 |
| PSA | 26.02000 |
| LogP | 1.15 |
| Vapour Pressure | 0.6±0.4 mmHg at 25°C |
| Index of Refraction | 1.548 |
| InChIKey | KRZCOLNOCZKSDF-UHFFFAOYSA-N |
| SMILES | Nc1ccc(F)cc1 |
| Stability | Stable. Incompatible with acids, oxidizing agents. |
| Water Solubility | 33 g/L (20 ºC) |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 417 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 umol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 77,317,1980
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 1 umol/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 77,317,1980
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R22;R36/38 |
| Safety Phrases | S26-S36/37/39-S45-S37/39 |
| RIDADR | UN 2941 6.1/PG 3 |
| WGK Germany | 1 |
| RTECS | BY1575000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 29214210 |
Customs
| HS Code | 29214210 |
|---|
Articles18
More Articles| Growth of Thin, Anisotropic, π-Conjugated Molecular Films by Stepwise "Click" Assembly of Molecular Building Blocks: Characterizing Reaction Yield, Surface Coverage, and Film Thickness versus Addition Step Number. J. Am. Chem. Soc. 137 , 8819-28, (2015) We report the systematic characterization of anisotropic, π-conjugated oligophenyleneimine (OPI) films synthesized using stepwise imine condensation, or "click" chemistry. Film synthesis began with a ... | |
| Biopartitioning micellar chromatography to predict mutagenicity of aromatic amines. Eur. J. Med. Chem. 42 , 1396-402, (2007) Mutagenicity is a toxicity endpoint associated with the chronic exposure to chemicals. Aromatic amines have considerable industrial and environmental importance due to their widespread use in industry... | |
| The many roles for fluorine in medicinal chemistry. J. Med. Chem. 51 , 4359-69, (2008) |
Synonyms
| P-FLUOROANILINE |
| 4-Fluoroaniline |
| 4-fluoro-anilin |
| 4-fluoro-aniline |
| MFCD00007829 |
| Benzenamine, 4-fluoro- |
| 4-fluoro-phenylamine |
| fluoroanilines |
| p-fluoro-anilin |
| 4-fluorobenzeneamine |
| 4-Fluoronaniline |
| 4-Fluoranilin |
| EINECS 206-735-5 |
| Ezetimibe Impurity 18 |
