CAS 371-41-5|4-Fluorophenol
Introduction：Basic information about CAS 371-41-5|4-Fluorophenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Fluorophenol | ||
|---|---|---|---|
| CAS Number | 371-41-5 | Molecular Weight | 112.102 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 183.3±13.0 °C at 760 mmHg |
| Molecular Formula | C6H5FO | Melting Point | 43-46 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 68.3±0.0 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 4-Fluorophenol |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 183.3±13.0 °C at 760 mmHg |
| Melting Point | 43-46 °C(lit.) |
| Molecular Formula | C6H5FO |
| Molecular Weight | 112.102 |
| Flash Point | 68.3±0.0 °C |
| Exact Mass | 112.032440 |
| PSA | 20.23000 |
| LogP | 1.77 |
| Vapour Pressure | 0.6±0.4 mmHg at 25°C |
| Index of Refraction | 1.523 |
| InChIKey | RHMPLDJJXGPMEX-UHFFFAOYSA-N |
| SMILES | Oc1ccc(F)cc1 |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
| Water Solubility | 50 g/L |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 312 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 gm/kg/25W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 19,413,1959 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 1 gm/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 41,43,1990
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302-H312-H315-H319-H332-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R20/21/22;R36/37/38;R52/53 |
| Safety Phrases | S26-S37/39-S61 |
| RIDADR | UN 2928 6.1/PG 2 |
| WGK Germany | 1 |
| RTECS | SL4550000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 29081000 |
Customs
| HS Code | 2908199090 |
|---|---|
| Summary | HS: 2908199090. derivatives of polyphenols or phenol-alcohols containing only halogen substituents and their salts. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tariff:5.5%. general tariff:30.0% |
Articles19
More Articles| Atmospheric pressure chemical ionization of fluorinated phenols in atmospheric pressure chemical ionization mass spectrometry, tandem mass spectrometry, and ion mobility spectrometry. J. Am. Soc. Mass Spectrom. 10(11) , 1157-65, (1999) Atmospheric pressure chemical ionization (APCI)-mass spectrometry (MS) for fluorinated phenols (C6H5-xFxOH Where x = 0-5) in nitrogen with Cl- as the reagent ion yielded product ions of M Cl- through ... | |
| Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins Bioorg. Med. Chem. 17 , 896-904, (2009) This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoret... | |
| Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study. J. Med. Chem. 48 , 7234-42, (2005) In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas... |
Synonyms
| 4-fluoranylphenol |
| p-Fluorophenol |
| Phenol, p-fluoro- |
| Phenol,p-fluoro |
| MFCD00002316 |
| 4-Fluorophenol |
| phenol,4-fluoro |
| PARA-FLUOROPHENOL |
| 4-Fluoro-phenol |
| QR DF |
| 4-Fluorophenyl alcohol |
| EINECS 206-736-0 |
| Phenol, 4-fluoro- |
