CAS 24544-04-5|2,6-Diisopropylaniline

Introduction：Basic information about CAS 24544-04-5|2,6-Diisopropylaniline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2,6-Diisopropylaniline BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles10
8. Synonyms

Common Name	2,6-Diisopropylaniline
CAS Number	24544-04-5	Molecular Weight	177.29
Density	0.9±0.1 g/cm3	Boiling Point	257.3±9.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₉N	Melting Point	−45 °C(lit.)
MSDS	ChineseUSA	Flash Point	123.9±0.0 °C

Names

Name	2,6-di(propan-2-yl)aniline
Synonym	More Synonyms

2,6-Diisopropylaniline BiologicalActivity

Description	2,6-Diisopropylaniline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	2,6-Diisopropylaniline 用作生产碳化二亚胺稳定剂、合成树脂、抗氧化剂和药物活性成分的中间体。它还用于制备多主题席夫碱配体前体和 4,5-b is(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene。与三乙酰甲烷缩合生成-[1-(2,6-二异丙基苯基氨基)乙烯]戊烷-2,4-二酮。此外，它还用于制备 N-杂环卡宾络合物，用于无环酮的 α-芳基化、卤代芳烃的胺化和水性铃木偶联。除此之外，它还用于制备基于萘二酰亚胺的有机催化剂。

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	257.3±9.0 °C at 760 mmHg
Melting Point	−45 °C(lit.)
Molecular Formula	C₁₂H₁₉N
Molecular Weight	177.29
Flash Point	123.9±0.0 °C
Exact Mass	177.151749
PSA	26.02000
LogP	3.61
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.526
InChIKey	WKBALTUBRZPIPZ-UHFFFAOYSA-N
SMILES	CC(C)c1cccc(C(C)C)c1N
Water Solubility	<0.20 g/L

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX4025000

CHEMICAL NAME :: Aniline, 2,6-diisopropyl-

CAS REGISTRY NUMBER :: 24544-04-5

BEILSTEIN REFERENCE NO. :: 2208763

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H19-N

MOLECULAR WEIGHT :: 177.32

WISWESSER LINE NOTATION :: 1Y1&R BZ CY1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3204 mg/kg

TOXIC EFFECTS :: Liver - other changes Blood - changes in bone marrow (not otherwise specified) Blood - changes in spleen

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 3,285,1983 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4005 mg/kg/5D-C

TOXIC EFFECTS :: Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 3,285,1983

Safety Information

Hazard Statements	H412
Precautionary Statements	P273
Personal Protective Equipment	Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S61-S37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	BX4025000
HS Code	29214980

Customs

HS Code	2921420090
Summary	HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles10

Organo-palladium(II) complexes bearing unsymmetrical N,N,N-pincer ligands: synthesis, structures and oxidatively induced coupling reactions.

Dalton Trans. 44(16) , 7230-41, (2015)

The 2-(2′-aniline)-6-imine-pyridines, 2-(C6H4-2′-NH2)-6-(CMe=NAr)C5H3N (Ar = 4-i-PrC6H4 (HL1a), 2,6-i-Pr2C6H3 (HL1b)), have been synthesised via sequential Stille cross-coupling, deprotection and cond...

O,N,N-pincer ligand effects on oxidatively induced carbon-chlorine coupling reactions at palladium.

Dalton Trans. 44(13) , 6040-51, (2015)

The syntheses of two families of sterically tuneable O,N,N pro-ligands are reported, namely the 2-(phenyl-2'-ol)-6-imine-pyridines, 2-(C6H4-2'-OH),6-(CMe=NAr)C5H3N [Ar = 4-i-PrC6H4 (HL1(a)), 2,6-i-Pr2...

Rigid NON- and NSN-ligand complexes of tetravalent and trivalent uranium: comparison of U-OAr2 and U-SAr2 bonding.

Dalton Trans. 41(26) , 8175-89, (2012)

A rigid NSN-donor proligand, 4,5-bis(2,6-diisopropylanilino)-2,7-di-tert-butyl-9,9-dimethylthioxanthene (H(2)[TXA(2)], 1) was prepared by palladium-catalyzed coupling of 2,6-diisopropylaniline with 4,...

Synonyms

2,5-DIHYDRO-5-OXO-1-(3-TRIFLUOROMETHYLPHENYL)-1H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID DIMETHYLAMIDE

2,6-Diisopropylaniline (DIPA)

Aniline,2,6-diisopropyl

EINECS 246-305-4

2,6-Dilsopropylaniline

2,6-bis(1-methylethyl)aniline

2,6-Diisopropyl-phenylamine

2,6-bis(1-methylethyl)benzenamine

2,6-DIISOPROPYLPHENYLAMINE

MFCD00008887

2,6-(i-Pr)2PhNH2

2,6-di(propan-2-yl)aniline

(2,6-iPr2C6H3)NH2

Benzenamine, 2,6-bis(1-methylethyl)-

2,6-Diisopropylaniline

Benzenamine,2,6-bis(1-methylethyl)

2,6-di-i-propylaniline

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