CAS 72573-82-1|GADOTERIC ACID

Introduction：Basic information about CAS 72573-82-1|GADOTERIC ACID, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. GADOTERIC ACID BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	GADOTERIC ACID
CAS Number	72573-82-1	Molecular Weight	558.64200
Density	/	Boiling Point	701.6ºC at 760 mmHg
Molecular Formula	C₁₆H₂₅GdN₄O₈	Melting Point	/
MSDS	/	Flash Point	378.1ºC

Names

Name	Gadoteric acid
Synonym	More Synonyms

GADOTERIC ACID BiologicalActivity

Description	Gadoteric acid is a macrocyclic, paramagnetic, gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI) of the brain, spine, and related tissues. In particular, Gadoteric acid is able to detect and visualize areas of blood-brain barrier disruption and abnormal vascular distribution[1][2].
Related Catalog	Research Areas >>CancerResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others
In Vitro	在肝细胞癌（尤其是高血管病变）的 DCE-MRI 中，Gadoteric acid 提供了更好的，更明显的对比度，以及早期增强的可感知性和更强的冲洗性[1]。
References	[1]. Federico Collettini, et al. MR imaging of hepatocellular carcinoma: prospective intraindividual head-to-head comparison of the contrast agents gadoxetic acid and gadoteric acid. Sci Rep. 2022 Nov 3;12(1):18583. [2]. Martin Maurer, et al. Tolerability and diagnostic value of gadoteric acid in the general population and in patients with risk factors: results in more than 84,000 patients. Eur J Radiol. 2012 May;81(5):885-90.

Chemical & Physical Properties

Boiling Point	701.6ºC at 760 mmHg
Molecular Formula	C₁₆H₂₅GdN₄O₈
Molecular Weight	558.64200
Flash Point	378.1ºC
Exact Mass	559.09100
PSA	160.93000
InChIKey	GFSTXYOTEVLASN-UHFFFAOYSA-K
SMILES	O=C([O-])CN1CCN(CC(=O)[O-])CCN(CC(=O)O)CCN(CC(=O)[O-])CC1.[Gd+3]
Storage condition	2-8°C

Synonyms

Gadolinium 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetic acid

Gadoteric

gadolinium(III) 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid

Recommended......