Introduction：Basic information about CAS 2752-17-2|2,2-Oxybis(ethylamine), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,2-Oxybis(ethylamine) |
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| CAS Number | 2752-17-2 | Molecular Weight | 104.151 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 185.9±15.0 °C at 760 mmHg |
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| Molecular Formula | C4H12N2O | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 74.8±14.1 °C |
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Names
| Name | 2-(2-aminoethoxy)ethanamine |
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| Synonym | More Synonyms |
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2,2-Oxybis(ethylamine) BiologicalActivity
| Description | 22-Oxybis(ethylamine) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 185.9±15.0 °C at 760 mmHg |
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| Molecular Formula | C4H12N2O |
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| Molecular Weight | 104.151 |
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| Flash Point | 74.8±14.1 °C |
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| Exact Mass | 104.094963 |
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| PSA | 61.27000 |
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| LogP | -1.23 |
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| Vapour Pressure | 0.7±0.4 mmHg at 25°C |
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| Index of Refraction | 1.455 |
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| InChIKey | GXVUZYLYWKWJIM-UHFFFAOYSA-N |
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| SMILES | NCCOCCN |
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Safety Information
| Hazard Codes | C: Corrosive; |
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| Risk Phrases | R34 |
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| Safety Phrases | 45-36/37/39-26 |
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| RIDADR | 2735.0 |
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| Hazard Class | 8.0 |
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| HS Code | 2922199090 |
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Customs
| HS Code | 2922199090 |
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| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| 2,2'-Oxydiethanamine |
| GXVUZYLYWKWJIM-UHFFFAOYSA |
| diamino-PEG |
| EINECS 220-395-5 |
| Ethanamine, 2,2'-oxybis- |
| 2,2'-Oxydiethylamine |
| Bis(2-aminoethyl) Ether |
| 2,2′-Oxybis(ethylamine) |
| 2,2-Oxybis(ethylamine) |
| 1,5-diamino-3-oxa-pentane |
| 2,2'-Oxybis(ethylamine) |
| 2,2‘-Oxybis(ethylamine) |
| 2-(2-Aminoethoxy)ethylamine |
| 2-aminoethyl ether |
| Ethanamine,2,2'-oxybis |
| 2,2'-Diaminodiethyl Ether |
| 2,2'-DITHIOBISBENZOIC ACID |
