CAS 88515-58-6|Rosamultin

Introduction:Basic information about CAS 88515-58-6|Rosamultin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameRosamultin
CAS Number88515-58-6Molecular Weight650.84000
Density1.31g/cm3Boiling Point741.5ºC at 760 mmHg
Molecular FormulaC36H58O10Melting Point/
MSDS/Flash Point223.6ºC

Names

NameRosamultin
SynonymMore Synonyms

Rosamultin BiologicalActivity

DescriptionRosamultin is a 19 α-hydroxyursane-type triterpenoid isolated from Potentilla anserina L. Rosamultin has inhibitory effects against HIV-1 protease[1]. Rosamultin has the potential for treating H2O2-induced oxidative stress injury through its antioxidant and antiapoptosis effects[2].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Metabolic Enzyme/Protease >>HIV Protease
Target

IC50: HIV-1 protease[1]

In VitroRosamultin isolated from the root of R. rugosa inhibits HIV-1 protease by 53% at a concentration of 100 μM[1].
References

[1]. Zhang L, et al. Protective Effect of Rosamultin against H2O2-Induced Oxidative Stress and Apoptosis in H9c2 Cardiomyocytes.Oxid Med Cell Longev. 2018 Jul 16;2018:8415610.

[2]. Park JC, et al. Anti-HIV protease activity from rosa family plant extracts and rosamultin from Rosa rugosa.J Med Food. 2005 Spring;8(1):107-9.

Chemical & Physical Properties

Density1.31g/cm3
Boiling Point741.5ºC at 760 mmHg
Molecular FormulaC36H58O10
Molecular Weight650.84000
Flash Point223.6ºC
Exact Mass650.40300
PSA177.14000
LogP2.43370
Index of Refraction1.604
InChIKeyMLKQAGPAYHTNQQ-BRDPIYJESA-N
SMILESCC1CCC2(C(=O)OC3OC(CO)C(O)C(O)C3O)CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C)C5CCC43C)C2C1(C)O

Synonyms

Tormentic acid glucosyl
Rosamutin
ursolazuroside 1
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