Introduction：Basic information about CAS 52443-21-7|Glucametacine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Glucametacine |
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| CAS Number | 52443-21-7 | Molecular Weight | 518.94 |
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| Density | 1.44 | Boiling Point | 793.7ºC at 760mmHg |
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| Molecular Formula | C25H27ClN2O8 | Melting Point | / |
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| MSDS | / | Flash Point | 433.8ºC |
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Names
| Name | 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide |
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| Synonym | More Synonyms |
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Glucametacine BiologicalActivity
| Description | Glucametacine is an anti-inflammatory agent[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Guimarães SA, Assessment of the antiexudative and antiproliferative activities of non-steroidal anti-inflammatory drugs in inflammatory models developed in rats by subcutaneous implantation of bacterial cell walls from the dental plaque. Inflammation. 1996 Dec;20(6):623-36. |
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Chemical & Physical Properties
| Density | 1.44 |
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| Boiling Point | 793.7ºC at 760mmHg |
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| Molecular Formula | C25H27ClN2O8 |
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| Molecular Weight | 518.94 |
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| Flash Point | 433.8ºC |
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| Exact Mass | 536.15600 |
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| PSA | 159.71000 |
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| LogP | 1.08540 |
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| Index of Refraction | 1.634 |
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| InChIKey | XLVXAUNDHWERBM-IVGWJTKZSA-N |
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| SMILES | COc1ccc2c(c1)c(CC(=O)NC(C=O)C(O)C(O)C(O)CO)c(C)n2C(=O)c1ccc(Cl)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- LZ6775000
- CHEMICAL NAME :
- D-Glucose, 2-(((1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol- 3-yl)acetyl)amino)-2- deoxy-, hydrate
- CAS REGISTRY NUMBER :
- 52443-21-7
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C25-H27-Cl-N2-O8.H2-O
- MOLECULAR WEIGHT :
- 537.01
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 84 mg/kg/14D-I
- TOXIC EFFECTS :
- Behavioral - headache Gastrointestinal - other changes
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,435,1975
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Synonyms
| Glucametacina [INN-Spanish] |
| Glucametacin |
| Teoremac |
| Glucometacin |
| Glucametacine |
| Glucametacine [INN-French] |
| UNII-N1EXE5EHAN |
| Glucametacin [INN] |
| Glucametacinum [INN-Latin] |
| EINECS 257-923-9 |
