Introduction：Basic information about CAS 51146-55-5|2-Hydroxy Ibuprofen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Hydroxy Ibuprofen |
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| CAS Number | 51146-55-5 | Molecular Weight | 222.28000 |
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| Density | 1.125 g/cm3 | Boiling Point | 369.4ºC at 760 mmHg |
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| Molecular Formula | C13H18O3 | Melting Point | 120-122ºC |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | rac 2-Hydroxy Ibuprofen |
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| Synonym | More Synonyms |
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2-Hydroxy Ibuprofen BiologicalActivity
| Description | 2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX |
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| References | [1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. |
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Chemical & Physical Properties
| Density | 1.125 g/cm3 |
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| Boiling Point | 369.4ºC at 760 mmHg |
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| Melting Point | 120-122ºC |
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| Molecular Formula | C13H18O3 |
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| Molecular Weight | 222.28000 |
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| Exact Mass | 222.12600 |
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| PSA | 57.53000 |
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| LogP | 2.18810 |
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| Index of Refraction | 1.543 |
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| InChIKey | UJHKVYPPCJBOSG-UHFFFAOYSA-N |
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| SMILES | CC(C(=O)O)c1ccc(CC(C)(C)O)cc1 |
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| Storage condition | -20°C Freezer |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| HS Code | 2918199090 |
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Customs
| HS Code | 2918199090 |
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| Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| 2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propionic acid |
| 2-[4-(2-hydroxy-2-methylpropyl)phenyl]propanoic acid |
| 2-Hydroxyibuprofen |
| Ibuprofen Impurity 19 |
