CAS 18865-38-8|Glycinexylidide

Introduction：Basic information about CAS 18865-38-8|Glycinexylidide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameGlycinexylidide
CAS Number18865-38-8Molecular Weight178.23
Density1.122g/cm3Boiling Point323.5ºC at 760mmHg
Molecular FormulaC10H14N2OMelting Point92 °C
MSDS/Flash Point149.4ºC

Names

Nameglycinexylidide
SynonymMore Synonyms

Glycinexylidide BiologicalActivity

DescriptionGlycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local anesthetic that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease[1].
Related CatalogSignaling Pathways >>Membrane Transporter/Ion Channel >>Sodium ChannelResearch Areas >>CancerSignaling Pathways >>MAPK/ERK Pathway >>MEKSignaling Pathways >>MAPK/ERK Pathway >>ERKSignaling Pathways >>Stem Cell/Wnt >>ERK
References

[1]. Strong JM, et al. Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide. Clin Pharmacol Ther. 1975 Feb;17(2):184-94.  

Chemical & Physical Properties

Density1.122g/cm3
Boiling Point323.5ºC at 760mmHg
Melting Point92 °C
Molecular FormulaC10H14N2O
Molecular Weight178.23
Flash Point149.4ºC
Exact Mass178.11100
PSA55.12000
LogP1.97390
Vapour Pressure0.000261mmHg at 25°C
InChIKeyIXYVBZOSGGJWCW-UHFFFAOYSA-N
SMILESCc1cccc(C)c1NC(=O)CN

Safety Information

HS Code2924299090

Customs

HS Code2924299090
Summary2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

Glycinexylidide
2-AMINO-N-(2,6-DIMETHYLPHENYL)ACETAMIDE
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