CAS 563-68-8|thallium(I) acetate
Introduction：Basic information about CAS 563-68-8|thallium(I) acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | thallium(I) acetate | ||
|---|---|---|---|
| CAS Number | 563-68-8 | Molecular Weight | 263.42700 |
| Density | 3.77 | Boiling Point | / |
| Molecular Formula | C2H3O2Tl | Melting Point | 124-128 °C |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | thallium(I) acetate |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 3.77 |
|---|---|
| Melting Point | 124-128 °C |
| Molecular Formula | C2H3O2Tl |
| Molecular Weight | 263.42700 |
| Exact Mass | 263.98800 |
| PSA | 26.30000 |
| LogP | 0.01380 |
| InChIKey | HQOJMTATBXYHNR-UHFFFAOYSA-M |
| SMILES | CC(=O)[O-].[Tl+] |
| Storage condition | Store at RT. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 12 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Skin and Appendages - hair Behavioral - anorexia (human) Kidney, Ureter, Bladder - urine volume decreased
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 8 mg/kg
- TOXIC EFFECTS :
- Skin and Appendages - hair Behavioral - anorexia (human) Kidney, Ureter, Bladder - urine volume decreased
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Human - child
- DOSE/DURATION :
- 1400 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cough Gastrointestinal - hypermotility, diarrhea
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 41300 ug/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Gastrointestinal - other changes Blood - hemorrhage
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 35 mg/kg
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 37 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 13 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 17 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 26 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 9 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 45 mg/kg/7D-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - monoamine oxidase
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg/10D-I
- TOXIC EFFECTS :
- Brain and Coverings - other degenerative changes Vascular - regional or general arteriolar constriction Biochemical - Neurotransmitters or modulators (putative) - dopamine at other sites
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 58823 ug/kg/5D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 30 mg/kg
- SEX/DURATION :
- female 6-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
MUTATION DATA - TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,193,1979 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Tl)/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-TURKEY:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0567 No. of Facilities: 2 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 285 (estimated) No. of Female Employees: 206 (estimated)
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - hamster Embryo
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,193,1979 *** REVIEWS *** ACGIH TLV-TWA 0.1 mg(Tl)/m3 (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.1 mg(Tl)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.1 mg(Tl)/m3 JAN 1993 OEL-TURKEY:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg(Tl)/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0567 No. of Facilities: 2 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 285 (estimated) No. of Female Employees: 206 (estimated)
Safety Information
| Symbol | GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H300-H330-H373-H411 |
| Precautionary Statements | P260-P264-P273-P284-P301 + P310-P310 |
| Hazard Codes | T+,N |
| Risk Phrases | R26/28:Very Toxic by inhalation and if swallowed . R33:Danger of cumulative effects. R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . |
| Safety Phrases | S13-S28-S45-S61 |
| RIDADR | UN 1707 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | AJ5425000 |
| Packaging Group | II |
| Hazard Class | 6.1 |
Articles23
More Articles| The use of thallium diethyldithiocarbamate for mapping CNS potassium metabolism and neuronal activity: Tl+ -redistribution, Tl+ -kinetics and Tl+ -equilibrium distribution. J. Neurochem. 122(1) , 106-14, (2012) The potassium (K(+)) analogue thallium (Tl(+)) can be used as a tracer for mapping neuronal activity. However, because of the poor blood-brain barrier (BBB) K(+) -permeability, only minute amounts of ... | |
| [Action of the salts of univalent thallium on the liver mitochondria of the rat]. Zh. Evol. Biokhim. Fiziol. 20(4) , 353-5, (1984) Using light scattering and electron microscopic techniques, studies have been made of the swelling of liver mitochondria in isotonic sucrose solutions containing different concentrations of nitrate or... | |
| Acute toxicity of trivalent thallium compounds to Daphnia magna. Ecotoxicol. Environ. Saf. 61(3) , 432-5, (2005) Daphnia magna was used to evaluate the aquatic toxicity of Tl(III) compounds including Tl(III) nitrate, Tl(III) chloride, and Tl(III) acetate. The results clearly show that Tl(III) is extremely toxic ... |
Synonyms
| EINECS 209-257-5 |
| Thallium(III) acetate |
| thallium(l) acetate |
| thallium acetate |
| THALLIUM(I) ACETATE |
| Thallium triacetate |
| acetic acid,thallium acetate |
| (Parent) |
| Triacetatothallium(III) |
| thallous acetate |
| MFCD00013045 |
| Thallium(III) triacetate |
| Thallic triacetate |
| Thallic acetate sesquihydrate |
| Acetic acid,thallium(3+) salt |
| Essigsaeure,Thalliumacetat |
| Thallium(3+) acetate |
| thalium(III) acetate |
| Acetic Acid Thallium(1+) Salt |
| Tris(acetato)thallium |
| acetic acid,thallium(I)-acetate |
