Introduction：Basic information about CAS 17290-70-9|Isosinensetin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isosinensetin |
|---|
| CAS Number | 17290-70-9 | Molecular Weight | 372.369 |
|---|
| Density | 1.244±0.06 g/cm3 (20 ºC 760 Torr) | Boiling Point | 565.3±50.0 °C at 760 mmHg |
|---|
| Molecular Formula | C20H20O7 | Melting Point | 198-199 ºC |
|---|
| MSDS | / | Flash Point | 248.4±30.2 °C |
|---|
Names
| Name | 2-(3,4-dimethoxyphenyl)-5,7,8-trimethoxychromen-4-one |
|---|
| Synonym | More Synonyms |
|---|
Isosinensetin BiologicalActivity
| Description | Isosinensetin, a polymethoxylated flavone extracted from pericarpium citri reticulatae viride, exhibits inhibition on P-glycoprotein (P-gp) in MDR1-MDCKII cells[1][2]. |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Membrane Transporter/Ion Channel >>P-glycoprotein |
|---|
| Target | P-glycoprotein[2] |
|---|
| References | [1]. Wang D, et al. Identification of polymethoxylated flavones from green tangerine peel (Pericarpium Citri Reticulatae Viride) by chromatographic and spectroscopic techniques. J Pharm Biomed Anal. 2007 May 9;44(1):63-9. [2]. Bai J, et al. Inhibitory effects of flavonoids on P-glycoprotein in vitro and in vivo: Food/herb-drug interactions and structure-activity relationships. Toxicol Appl Pharmacol. 2019 Apr 15;369:49-59. |
|---|
Chemical & Physical Properties
| Density | 1.244±0.06 g/cm3 (20 ºC 760 Torr) |
|---|
| Boiling Point | 565.3±50.0 °C at 760 mmHg |
|---|
| Melting Point | 198-199 ºC |
|---|
| Molecular Formula | C20H20O7 |
|---|
| Molecular Weight | 372.369 |
|---|
| Flash Point | 248.4±30.2 °C |
|---|
| Exact Mass | 372.120911 |
|---|
| PSA | 76.36000 |
|---|
| LogP | 2.88 |
|---|
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
|---|
| Index of Refraction | 1.566 |
|---|
| InChIKey | UYCWETIUOAGWIL-UHFFFAOYSA-N |
|---|
| SMILES | COc1ccc(-c2cc(=O)c3c(OC)cc(OC)c(OC)c3o2)cc1OC |
|---|
Safety Information
| Hazard Codes | Xi |
|---|
| HS Code | 2932999099 |
|---|
Customs
| HS Code | 2932999099 |
|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| 2-(3,4-Dimethoxyphenyl)-5,7,8-trimethoxy-4H-chromen-4-one |
| 6-Demethoxynobiletin |
| UNII-63Z99S38LE |
| 5,7,8,3',4'-pentamethoxyflavone |
| Isosinensetin |
| 3',4',5,7,8-Pentamethoxyflavone |
| 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,7,8-trimethoxy- |
