CAS 2381-85-3|Nile Blue chloride

Introduction:Basic information about CAS 2381-85-3|Nile Blue chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameNile Blue chloride
CAS Number2381-85-3Molecular Weight353.84500
Density/Boiling Point487.9ºC at 760mmHg
Molecular FormulaC20H20ClN3OMelting Point>250°C
MSDSChineseFlash Point248.8ºC

Names

Namenile blue A
SynonymMore Synonyms

Nile Blue chloride BiologicalActivity

DescriptionNile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics[1][2].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. QM Ali, et al. Z-scan determination of the third-order optical nonlinearity of organic dye nile blue chloride. Modern Physics Letters B. 2006, 623-632.

[2]. Martinez V, et al. Nile Red and Nile Blue: Applications and Syntheses of Structural Analogues. Chemistry. 2016 Sep 19;22(39):13764-13782.

Chemical & Physical Properties

Boiling Point487.9ºC at 760mmHg
Melting Point>250°C
Molecular FormulaC20H20ClN3O
Molecular Weight353.84500
Flash Point248.8ºC
Exact Mass353.12900
PSA55.06000
LogP1.06520
InChIKeySHXOKQKTZJXHHR-UHFFFAOYSA-N
SMILESCC[N+](CC)=c1ccc2nc3c(cc(N)c4ccccc43)oc-2c1.[Cl-]
Water SolubilitySolubility Soluble in water, ethanol

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ1930000
CHEMICAL NAME :
Benzo(a)phenoxazin-7-ium, 5-amino-9-(diethylamino)-, chloride
CAS REGISTRY NUMBER :
2381-85-3
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H20-N3-O.Cl
MOLECULAR WEIGHT :
353.88
WISWESSER LINE NOTATION :
T D6 B666 CN JOJ GN2&2 MZ &G &15/28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
33 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Microorganism - not otherwise specified
DOSE/DURATION :
1 ppm
REFERENCE :
POASAD Proceedings of the Oklahoma Academy of Science. (Oklahoma Academy of Science, c/o Executive Secretary-Treasurer, Southwestern Oklahoma State Univ., Weatherford, OK 73096) V.1- 1910/1920- Volume(issue)/page/year: 34,114,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4350 No. of Facilities: 71 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 3549 (estimated) No. of Female Employees: 1329 (estimated)

Safety Information

Hazard CodesXi
Safety PhrasesS22-S24/25
WGK Germany3
RTECSDJ1930000

Synonyms

NILE BLUE CHLORIDE
EINECS 219-181-4
Nile Blue BX
nilebluebase
cresolfastviolet
nile blue B
nileblueax
BASIC BLUE 12
Nile Blue A
5-amino-9-diethylamino-benzo[a]phenoxazin-5-ylium,chloride
MFCD00011936
NILE BLUE A CHLORIDE
c.i.basicblue12
5-amino-9-diethylamino-benzo[a]phenoxazinylium,chloride
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