Introduction:Basic information about CAS 2381-85-3|Nile Blue chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Nile Blue chloride |
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| CAS Number | 2381-85-3 | Molecular Weight | 353.84500 |
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| Density | / | Boiling Point | 487.9ºC at 760mmHg |
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| Molecular Formula | C20H20ClN3O | Melting Point | >250°C |
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| MSDS | Chinese | Flash Point | 248.8ºC |
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Names
| Name | nile blue A |
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| Synonym | More Synonyms |
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Nile Blue chloride BiologicalActivity
| Description | Nile blue chloride is a highly fluorescent and photostable organic dye. Nile blue chloride and fluorescein isothiocyanate (FITC) can be used to construct a ratiometric pH sensitive probe for tracking the pH of the extracellular fluid between cancer cells in realtime. Nile Blue chloride has the potential for the research of nonlinear optics[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. QM Ali, et al. Z-scan determination of the third-order optical nonlinearity of organic dye nile blue chloride. Modern Physics Letters B. 2006, 623-632. [2]. Martinez V, et al. Nile Red and Nile Blue: Applications and Syntheses of Structural Analogues. Chemistry. 2016 Sep 19;22(39):13764-13782. |
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Chemical & Physical Properties
| Boiling Point | 487.9ºC at 760mmHg |
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| Melting Point | >250°C |
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| Molecular Formula | C20H20ClN3O |
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| Molecular Weight | 353.84500 |
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| Flash Point | 248.8ºC |
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| Exact Mass | 353.12900 |
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| PSA | 55.06000 |
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| LogP | 1.06520 |
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| InChIKey | SHXOKQKTZJXHHR-UHFFFAOYSA-N |
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| SMILES | CC[N+](CC)=c1ccc2nc3c(cc(N)c4ccccc43)oc-2c1.[Cl-] |
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| Water Solubility | Solubility Soluble in water, ethanol |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DJ1930000
- CHEMICAL NAME :
- Benzo(a)phenoxazin-7-ium, 5-amino-9-(diethylamino)-, chloride
- CAS REGISTRY NUMBER :
- 2381-85-3
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C20-H20-N3-O.Cl
- MOLECULAR WEIGHT :
- 353.88
- WISWESSER LINE NOTATION :
- T D6 B666 CN JOJ GN2&2 MZ &G &15/28
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 33 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
MUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Microorganism - not otherwise specified
- DOSE/DURATION :
- 1 ppm
- REFERENCE :
- POASAD Proceedings of the Oklahoma Academy of Science. (Oklahoma Academy of Science, c/o Executive Secretary-Treasurer, Southwestern Oklahoma State Univ., Weatherford, OK 73096) V.1- 1910/1920- Volume(issue)/page/year: 34,114,1953 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4350 No. of Facilities: 71 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 3549 (estimated) No. of Female Employees: 1329 (estimated)
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Safety Information
| Hazard Codes | Xi |
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| Safety Phrases | S22-S24/25 |
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| WGK Germany | 3 |
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| RTECS | DJ1930000 |
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Synonyms
| NILE BLUE CHLORIDE |
| EINECS 219-181-4 |
| Nile Blue BX |
| nilebluebase |
| cresolfastviolet |
| nile blue B |
| nileblueax |
| BASIC BLUE 12 |
| Nile Blue A |
| 5-amino-9-diethylamino-benzo[a]phenoxazin-5-ylium,chloride |
| MFCD00011936 |
| NILE BLUE A CHLORIDE |
| c.i.basicblue12 |
| 5-amino-9-diethylamino-benzo[a]phenoxazinylium,chloride |