CAS 41653-73-0|Koaburaside

Introduction：Basic information about CAS 41653-73-0|Koaburaside, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Koaburaside BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Koaburaside
CAS Number	41653-73-0	Molecular Weight	332.303
Density	1.5±0.1 g/cm3	Boiling Point	599.0±50.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₀O₉	Melting Point	/
MSDS	/	Flash Point	316.1±30.1 °C

Names

Name	4-Hydroxy-3,5-dimethoxyphenyl β-D-glucopyranoside
Synonym	More Synonyms

Koaburaside BiologicalActivity

Description	Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase[1].
Related Catalog	Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Immunology/Inflammation >>Interleukin RelatedResearch Areas >>Inflammation/Immunology
References	[1]. He Y, et al. Phenolic compounds from Eurycorymbus cavaleriei. J Asian Nat Prod Res. 2011 Jun;13(6):575-80. [2]. Subedi L, et al. Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro. Phytomedicine. 2016 Jul 15;23(8):872-81. [3]. Choi HG, et al. Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities. Nat Prod Commun. 2013 Feb;8(2):181-2.

Description

Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase[1].

Related Catalog

Signaling Pathways >>Anti-infection >>Influenza VirusResearch Areas >>CancerResearch Areas >>InfectionSignaling Pathways >>Immunology/Inflammation >>Interleukin RelatedResearch Areas >>Inflammation/Immunology

References

[1]. He Y, et al. Phenolic compounds from Eurycorymbus cavaleriei. J Asian Nat Prod Res. 2011 Jun;13(6):575-80.

[2]. Subedi L, et al. Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro. Phytomedicine. 2016 Jul 15;23(8):872-81.

[3]. Choi HG, et al. Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities. Nat Prod Commun. 2013 Feb;8(2):181-2.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	599.0±50.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₀O₉
Molecular Weight	332.303
Flash Point	316.1±30.1 °C
Exact Mass	332.110718
PSA	138.07000
LogP	-1.60
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.609
InChIKey	SWHCKWOYUSDWOF-RGCYKPLRSA-N
SMILES	COc1cc(OC2OC(CO)C(O)C(O)C2O)cc(OC)c1O

Safety Information

Hazard Codes	Xi

Synonyms

Koaburaside

4-Hydroxy-3,5-dimethoxyphenyl Beta-D-glucopyranoside

β-D-Glucopyranoside, 4-hydroxy-3,5-dimethoxyphenyl

4-Hydroxy-3,5-dimethoxyphenyl β-D-glucopyranoside

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