Introduction：Basic information about CAS 23518-30-1|Licarin A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Licarin A |
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| CAS Number | 23518-30-1 | Molecular Weight | 326.386 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 452.0±45.0 °C at 760 mmHg |
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| Molecular Formula | C20H22O4 | Melting Point | / |
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| MSDS | / | Flash Point | 227.2±28.7 °C |
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Names
| Name | 2-Methoxy-4-{(2S,3S)-7-methoxy-3-methyl-5-[(1E)-1-propen-1-yl]-2, 3-dihydro-1-benzofuran-2-yl}phenol |
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| Synonym | More Synonyms |
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Licarin A BiologicalActivity
| Description | (±)-Licarin A ((±)-trans-Dehydrodiisoeugenol) is a dihydrobenzofuran neolignan, the resultant of an oxidative coupling reaction of isoeugenol and horseradish peroxidase (HRP) enzyme. (±)-Licarin A displays 58.7% parasite lysis and has an IC50 value of 100.8 µM for trypanocidal activity against trypomastigote forms of T. cruzi. And (±)-Licarin A shows 100% parasites mortality at 200 µM[1]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Meleti VR, et al. (±)-licarin A and its semi-synthetic derivatives: in vitro and in silico evaluation of trypanocidaland schistosomicidal activities. Acta Trop. 2019 Oct 29:105248. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 452.0±45.0 °C at 760 mmHg |
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| Molecular Formula | C20H22O4 |
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| Molecular Weight | 326.386 |
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| Flash Point | 227.2±28.7 °C |
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| Exact Mass | 326.151794 |
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| PSA | 47.92000 |
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| LogP | 4.19 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.596 |
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| InChIKey | ITDOFWOJEDZPCF-UHFFFAOYSA-N |
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| SMILES | CC=Cc1cc(OC)c2c(c1)C(C)C(c1ccc(O)c(OC)c1)O2 |
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Synonyms
| Isoeugenol,dehydrodi |
| 2-Methoxy-4-{(2S,3S)-7-methoxy-3-methyl-5-[(1E)-1-propen-1-yl]-2,3-dihydro-1-benzofuran-2-yl}phenol |
| DEHRODIISOEUGENOL |
| Phenol, 4-[(2S,3S)-2,3-dihydro-7-methoxy-3-methyl-5-[(1E)-1-propen-1-yl]-2-benzofuranyl]-2-methoxy- |
| Diisoeugenol,dehydro |
| Licarin A |
| dehydrodiisoeugenol |
