CAS 23971-42-8|Meranzin

Introduction：Basic information about CAS 23971-42-8|Meranzin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Meranzin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Meranzin
CAS Number	23971-42-8	Molecular Weight	260.285
Density	1.2±0.1 g/cm3	Boiling Point	414.8±45.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₆O₄	Melting Point	/
MSDS	/	Flash Point	185.3±28.8 °C

Names

Name	8-{[(2S)-3,3-Dimethyl-2-oxiranyl]methyl}-7-methoxy-2H-chromen-2-o ne
Synonym	More Synonyms

Meranzin BiologicalActivity

Description	Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression[1][2].
Related Catalog	Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Neurological Disease
References	[1]. Lan Li, et al. Chaihu-Shugan-San and Absorbed Meranzin Hydrate Induce Anti-Atherosclerosis and Behavioral Improvements in High-Fat Diet ApoE -/- Mice via Anti-Inflammatory and BDNF-TrkB Pathway. Biomed Pharmacother. 2019 Jul;115:108893. [2]. Rongwei Yan, et al. Preparative Isolation and Purification of Hainanmurpanin, Meranzin, and Phebalosin From Leaves of Murraya Exotica L. Using Supercritical Fluid Extraction Combined With Consecutive High-Speed Countercurrent Chromatography. J Sep Sci. 2018 May;41(9):2092-2101.

Description

Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2–BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression[1][2].

Related Catalog

Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Neurological Disease

References

[1]. Lan Li, et al. Chaihu-Shugan-San and Absorbed Meranzin Hydrate Induce Anti-Atherosclerosis and Behavioral Improvements in High-Fat Diet ApoE -/- Mice via Anti-Inflammatory and BDNF-TrkB Pathway. Biomed Pharmacother. 2019 Jul;115:108893.

[2]. Rongwei Yan, et al. Preparative Isolation and Purification of Hainanmurpanin, Meranzin, and Phebalosin From Leaves of Murraya Exotica L. Using Supercritical Fluid Extraction Combined With Consecutive High-Speed Countercurrent Chromatography. J Sep Sci. 2018 May;41(9):2092-2101.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	414.8±45.0 °C at 760 mmHg
Molecular Formula	C₁₅H₁₆O₄
Molecular Weight	260.285
Flash Point	185.3±28.8 °C
Exact Mass	260.104858
PSA	51.97000
LogP	1.92
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.567
InChIKey	LSZONYLDFHGRDP-LBPRGKRZSA-N
SMILES	COc1ccc2ccc(=O)oc2c1CC1OC1(C)C

Safety Information

Hazard Codes	Xi

Synonyms

pimelic acid monomethyl ester

8-{[(2S)-3,3-Dimethyl-2-oxiranyl]methyl}-7-methoxy-2H-chromen-2-one

6-methoxycarbonylhexanoic acid

methyl hydrogenpimelate

monomethyl heptanedioate

Heptanedioic acid,1-methyl ester

2H-1-Benzopyran-2-one, 8-[[(2S)-3,3-dimethyloxiranyl]methyl]-7-methoxy-

Heptanedioic acid,monomethyl ester

Methyl hydrogen heptane-1,7-dioate

Monomethyl pimelate

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