CAS 66648-43-9|N-trans-Feruloyltyramine
| Common Name | N-trans-Feruloyltyramine | ||
|---|---|---|---|
| CAS Number | 66648-43-9 | Molecular Weight | 313.348 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 554.2±60.0 °C at 760 mmHg |
| Molecular Formula | C18H19NO4 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 289.0±32.9 °C |
| Symbol | GHS09 | Signal Word | Warning |
Names
| Name | (2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]ac rylamide |
|---|---|
| Synonym | More Synonyms |
N-trans-Feruloyltyramine BiologicalActivity
| Description | N-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid from Piper nigru, is an inhibitor of COX1 and COX2, with potential antioxidant properties. N-trans-Feruloyltyramine possesses anti-inflammatory activity[1]. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Immunology/Inflammation >>COX |
| Target | COX-1 COX-2 |
| References | [1]. Aswad M, et al. Nature is the best source of anti-inflammatory drugs: indexing natural products for their anti-inflammatory bioactivity. Inflamm Res. 2018 Jan;67(1):67-75. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 554.2±60.0 °C at 760 mmHg |
| Molecular Formula | C18H19NO4 |
| Molecular Weight | 313.348 |
| Flash Point | 289.0±32.9 °C |
| Exact Mass | 313.131409 |
| PSA | 78.79000 |
| LogP | 3.33 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.566 |
| InChIKey | NPNNKDMSXVRADT-WEVVVXLNSA-N |
| SMILES | COc1cc(C=CC(=O)NCCc2ccc(O)cc2)ccc1O |
| Storage condition | ?20°C |
Safety Information
| Symbol | GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H410 |
| Precautionary Statements | P273-P501 |
| Hazard Codes | N |
| Risk Phrases | 50 |
| Safety Phrases | 61 |
| RIDADR | UN 3077 9 / PGIII |
Articles26
More Articles| Transgenic tomato plants overexpressing tyramine N-hydroxycinnamoyltransferase exhibit elevated hydroxycinnamic acid amide levels and enhanced resistance to Pseudomonas syringae. Mol. Plant Microbe Interact. 27(10) , 1159-69, (2014) Hydroxycinnamic acid amides (HCAA) are secondary metabolites involved in plant development and defense that have been widely reported throughout the plant kingdom. These phenolics show antioxidant, an... | |
| A feruloyltyramine trimer isolated from potato common scab lesions Phytochemistry 71(17-18) , 2187-9, (2010) Graphical abstract A lignanamide isolated from potato common scab lesions was characterized as a feruloyltyramine trimer by MS and NMR techniques. | |
| Endosperm-specific expression of serotonin N-hydroxycinnamoyltransferase in rice. Plant Foods Hum. Nutr. 63(2) , 53-7, (2008) Serotonin N-hydroxycinnamoyltransferase (SHT) is a key enzyme in the synthesis of feruloylserotonin (FS) and 4-coumaroylserotonin (CS). These serotonin derivatives show strong antioxidant activity, ma... |
Synonyms
| 6,7-dimethoxy-5-hydroxyflavone |
| 5-Hydroxy-6,7-dimethoxy-2-phenyl-4H-chromen-4-one |
| N-trans-Feruloyltyramine |
| (1E,2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-propenimidic acid |
| 5-Hydroxy-6,7-dimethoxyflavone |
| (2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide |
| 5-hydroxy-6,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one |
| 6,7-di-O-methyl-baicalein |
| moupinamide |
| 2-Propenimidic acid, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (1E,2E)- |
| 4H-1-Benzopyran-4-one,5-hydroxy-6,7-dimethoxy-2-phenyl |
| baicalein 6,7-dimethyl ether |
| 2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (2E)- |
| Mosloflavone |
