Introduction：Basic information about CAS 60796-64-7|Norbraylin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Norbraylin |
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| CAS Number | 60796-64-7 | Molecular Weight | 244.243 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 471.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C14H12O4 | Melting Point | / |
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| MSDS | / | Flash Point | 185.2±22.2 °C |
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Names
| Name | 6-Hydroxy-8,8-dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one |
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| Synonym | More Synonyms |
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Norbraylin BiologicalActivity
| Description | Norbraylin, a natural prenylated coumarin, is a PDE4D2 inhibitor with an IC50 value of 7.15 μM[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE)Research Areas >>Inflammation/Immunology |
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| Target | PDE4D2:7.15 μM (IC50) |
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| References | [1]. Lin Chen, et al. (P)/(M)-corinepalensin A, a pair of axially chiral prenylated bicoumarin enantiomers with a rare C-5C-5' linkage from the twigs of Coriaria nepalensis. Phytochemistry. 2018 May;149:140-145. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 471.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C14H12O4 |
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| Molecular Weight | 244.243 |
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| Flash Point | 185.2±22.2 °C |
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| Exact Mass | 244.073563 |
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| PSA | 59.67000 |
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| LogP | 2.72 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.612 |
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| InChIKey | OYPWMLRFDXSKJG-UHFFFAOYSA-N |
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| SMILES | CC1(C)C=Cc2c(c(O)cc3ccc(=O)oc23)O1 |
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Safety Information
Customs
| HS Code | 2932999099 |
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| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 6-Hydroxy-8,8-dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one |
| 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 6-hydroxy-8,8-dimethyl- |
