CAS 271576-80-8|SD-06

Introduction：Basic information about CAS 271576-80-8|SD-06, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. SD-06 BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	SD-06
CAS Number	271576-80-8	Molecular Weight	397.858
Density	1.4±0.1 g/cm3	Boiling Point	652.6±55.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀ClN₅O₂	Melting Point	/
MSDS	/	Flash Point	348.5±31.5 °C

Names

Name	1-[4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]piperidin-1-yl]-2-hydroxyethanone
Synonym	More Synonyms

SD-06 BiologicalActivity

Description	SD 0006 (SD-06) is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po).
Related Catalog	Signaling Pathways >>MAPK/ERK Pathway >>p38 MAPKResearch Areas >>Inflammation/Immunology
Target	IC50: 170 nM (p38MAPK).

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	652.6±55.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₀ClN₅O₂
Molecular Weight	397.858
Flash Point	348.5±31.5 °C
Exact Mass	397.130554
PSA	95.00000
LogP	1.50
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.638
InChIKey	CATQHDWESBRRQA-UHFFFAOYSA-N
SMILES	O=C(CO)N1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1

Synonyms

SD06

2-{4-[5-(4-Chlorophenyl)-4-Pyrimidin-4-Yl-1h-Pyrazol-3-Yl]piperidin-1-Yl}-2-Oxoethanol

1-{4-[5-(4-Chlorophenyl)-4-(4-pyrimidinyl)-1H-pyrazol-3-yl]-1-piperidinyl}-2-hydroxyethanone

SD-06

3hl7

N-(2-hydroxyacetyl)-5-(4-piperidyl)-4-(4-pyrimidinyl)-3-(4-chlorophenyl)pyrazole

Ethanone, 1-[4-[5-(4-chlorophenyl)-4-(4-pyrimidinyl)-1H-pyrazol-3-yl]-1-piperidinyl]-2-hydroxy-

2-{4-[3-(4-chlorophenyl)-4-pyrimidin-4-yl-1H-pyrazol-5-yl]piperidin-1-yl}-2-oxoethanol

1-{4-[5-(4-chlorophenyl)-4-(pyrimidin-4-yl)-1H-pyrazol-3-yl]piperidin-1-yl}-2-hydroxyethanone

Recommended......