Introduction：Basic information about CAS 412950-08-4|Rilapladib, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Rilapladib |
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| CAS Number | 412950-08-4 | Molecular Weight | 735.80500 |
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| Density | 1.36g/cm3 | Boiling Point | / |
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| Molecular Formula | C40H38F5N3O3S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-[2-[(2,3-difluorophenyl)methylsulfanyl]-4-oxoquinolin-1-yl]-N-[1-(2-methoxyethyl)piperidin-4-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide |
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| Synonym | More Synonyms |
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Rilapladib BiologicalActivity
| Description | Rilapladib is a selective Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) inhibitor with an IC50 of 230 pM. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>PhosphataseResearch Areas >>Neurological Disease |
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| Target | IC50: 230 pM (Lp-PLA2)[1]. |
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| References | [1]. Shaddinger BC, et al. Platelet aggregation unchanged by lipoprotein-associated phospholipase A₂ inhibition: results from an in vitro study and two randomized phase I trials. PLoS One. 2014 Jan 27;9(1):e83094. |
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Chemical & Physical Properties
| Density | 1.36g/cm3 |
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| Molecular Formula | C40H38F5N3O3S |
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| Molecular Weight | 735.80500 |
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| Exact Mass | 735.25500 |
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| PSA | 80.08000 |
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| LogP | 8.33530 |
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| InChIKey | NNBGCSGCRSCFEA-UHFFFAOYSA-N |
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| SMILES | COCCN1CCC(N(Cc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)C(=O)Cn2c(SCc3cccc(F)c3F)cc(=O)c3ccccc32)CC1 |
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| Storage condition | 2-8℃ |
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Synonyms
| MTdU |
| Rilapladib |
| UNII-O14CWE893Z |
