Introduction：Basic information about CAS 50656-77-4|Niranthin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Niranthin |
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| CAS Number | 50656-77-4 | Molecular Weight | 432.507 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 559.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C24H32O7 | Melting Point | / |
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| MSDS | / | Flash Point | 221.8±30.0 °C |
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Names
| Name | Niranthin |
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| Synonym | More Synonyms |
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Niranthin BiologicalActivity
| Description | Niranthin, a lignan with a wide spectrum of pharmacological activities. Niranthin is a potent and non-competitive inhibitor of heterodimeric type IB topoisomerase of L. donovani. Niranthin can be used for the research of drug-resistant leishmaniasis treatment[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>TopoisomeraseResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology |
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| Target | Topoisomerase |
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| References | [1]. Sayan Chowdhury, et al. The lignan niranthin poisons Leishmania donovani topoisomerase IB and favours a Th1 immune response in mice. EMBO Mol Med. 2012 Oct;4(10):1126-43. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 559.5±50.0 °C at 760 mmHg |
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| Molecular Formula | C24H32O7 |
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| Molecular Weight | 432.507 |
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| Flash Point | 221.8±30.0 °C |
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| Exact Mass | 432.214813 |
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| PSA | 64.61000 |
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| LogP | 4.40 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.534 |
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| InChIKey | RCFGIEPQSDGMJJ-RTBURBONSA-N |
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| SMILES | COCC(Cc1ccc(OC)c(OC)c1)C(COC)Cc1cc(OC)c2c(c1)OCO2 |
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Safety Information
Synonyms
| 1,3-Benzodioxole, 6-[(2R,3R)-4-(3,4-dimethoxyphenyl)-2,3-bis(methoxymethyl)butyl]-4-methoxy- |
| 6-[(2R,3R)-3-(3,4-Dimethoxybenzyl)-4-methoxy-2-(methoxymethyl)butyl]-4-methoxy-1,3-benzodioxole |
