CAS 66648-50-8|Ethyl caffeate

Introduction：Basic information about CAS 66648-50-8|Ethyl caffeate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Ethyl caffeate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Ethyl caffeate
CAS Number	66648-50-8	Molecular Weight	208.211
Density	1.3±0.1 g/cm3	Boiling Point	377.0±32.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₂O₄	Melting Point	/
MSDS	USA	Flash Point	148.4±18.6 °C

Names

Name	ethyl 3,4-dihydroxycinnamate
Synonym	More Synonyms

Ethyl caffeate BiologicalActivity

Description	Ethyl trans-caffeate is the trans form of Ethyl Caffeate (HY-N6966). Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse skin[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. Chiang YM, et al. Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br J Pharmacol. 2005 Oct;146(3):352-63.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	377.0±32.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₂O₄
Molecular Weight	208.211
Flash Point	148.4±18.6 °C
Exact Mass	208.073563
PSA	66.76000
LogP	1.72
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.612
InChIKey	WDKYDMULARNCIS-GQCTYLIASA-N
SMILES	CCOC(=O)C=Cc1ccc(O)c(O)c1
Storage condition	2-8℃

Safety Information

Hazard Codes	Xn
Risk Phrases	R36/37/38
Safety Phrases	S26-S36

Synonyms

Ethyl caffeate

MFCD00045754

caffeic acid ethyl ester

2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, ethyl ester

ethyl caffeoate

Ethyl 3-(3,4-dihydroxyphenyl)acrylate

E-Caffeic acid ethyl ester

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