CAS 27548-93-2|Baccatin III

Introduction：Basic information about CAS 27548-93-2|Baccatin III, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Baccatin III BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Baccatin III
CAS Number	27548-93-2	Molecular Weight	586.627
Density	1.4±0.1 g/cm3	Boiling Point	713.6±60.0 °C at 760 mmHg
Molecular Formula	C₃₁H₃₈O₁₁	Melting Point	229-234 °C
MSDS	/	Flash Point	226.9±26.4 °C

Names

Name	Baccatine III
Synonym	More Synonyms

Baccatin III BiologicalActivity

Description	Baccatin III is a natural product isolated from Pacific yew tree and related species. Baccatin III reduces tumor progression by inhibiting the accumulation and suppressive function of MDSCs[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
References	[1]. Lee YH, et al. Baccatin III, a precursor for the semisynthesis of paclitaxel, inhibits the accumulation and suppressive activity of myeloid-derived suppressor cells in tumor-bearing mice. Int Immunopharmacol. 2014 Aug;21(2):487-93.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	713.6±60.0 °C at 760 mmHg
Melting Point	229-234 °C
Molecular Formula	C₃₁H₃₈O₁₁
Molecular Weight	586.627
Flash Point	226.9±26.4 °C
Exact Mass	586.241394
PSA	165.89000
LogP	4.06
Vapour Pressure	0.0±2.4 mmHg at 25°C
Index of Refraction	1.605
InChIKey	OVMSOCFBDVBLFW-VHLOTGQHSA-N
SMILES	CC(=O)OC1C(=O)C2(C)C(O)CC3OCC3(OC(C)=O)C2C(OC(=O)c2ccccc2)C2(O)CC(O)C(C)=C1C2(C)C
Storage condition	2-8°C
Stability	4 Year Shelf Life

Safety Information

Hazard Codes	T: Toxic;
Risk Phrases	R45
Safety Phrases	53-22-26-36/37/39-45-24/25
RIDADR	1544
WGK Germany	3
Packaging Group	III
Hazard Class	6.1(b)

Synonyms

Baccatin III

MFCD00153921

(2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,7,13-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate

7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-

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