CAS 112362-50-2|Dalfopristin
Introduction：Basic information about CAS 112362-50-2|Dalfopristin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dalfopristin | ||
|---|---|---|---|
| CAS Number | 112362-50-2 | Molecular Weight | 690.84700 |
| Density | 1.27g/cm3 | Boiling Point | 940.5ºC at 760 mmHg |
| Molecular Formula | C34H50N4O9S | Melting Point | / |
| MSDS | / | Flash Point | 522.6ºC |
Names
| Name | Dalfopristin |
|---|
Dalfopristin BiologicalActivity
| Description | Dalfopristin is a semi-synthetic streptogramin antibiotic. Quinupristin/Dalfopristin (Q/D) is a valuable alternative antibiotic to vancomycin for the treatment of multi-drug resistant Enterococcus faecium infections. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
| Target | Antibacterial[1] |
| In Vitro | Quinupristin/Dalfopristin(Q/D) is a combination of streptogramins B (Quinupristin) and streptogramins A (Dalfopristin) at 30:70 ratio[1]. Quinupristin/Dalfopristin, a semisynthetic injectable streptogramin, is a combination of 2 synergistic antibiotic components that are derived from pristinamycin: a type B streptogramin (Quinupristin) and a type A streptogramin (Dalfopristin), in a 30:70 weight-to-weight ratio[2]. |
| References | [1]. Wang S, et al. Characteristic of Enterococcus faecium clinical isolates with quinupristin/Dalfopristin resistance in China. BMC Microbiol. 2016 Oct 21;16(1):246. [2]. Sacar M, et al. Comparison of antimicrobial agents as therapy for experimental endocarditis: caused by methicillin-resistant Staphylococcus aureus. Tex Heart Inst J. 2010;37(4):400-4. |
Chemical & Physical Properties
| Density | 1.27g/cm3 |
|---|---|
| Boiling Point | 940.5ºC at 760 mmHg |
| Molecular Formula | C34H50N4O9S |
| Molecular Weight | 690.84700 |
| Flash Point | 522.6ºC |
| Exact Mass | 690.33000 |
| PSA | 184.80000 |
| LogP | 3.61680 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.575 |
| InChIKey | SUYRLXYYZQTJHF-PSUTZUHDSA-N |
| SMILES | CCN(CC)CCS(=O)(=O)C1CCN2C(=O)c3coc(n3)CC(=O)CC(O)C=C(C)C=CCNC(=O)C=CC(C)C(C(C)C)OC(=O)C12 |
| Storage condition | 2-8℃ |
