CAS 32231-06-4|Methylenedioxybenzylpiperazine

Introduction：Basic information about CAS 32231-06-4|Methylenedioxybenzylpiperazine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles3
7. Synonyms

Common Name	Methylenedioxybenzylpiperazine
CAS Number	32231-06-4	Molecular Weight	220.268
Density	1.2±0.1 g/cm3	Boiling Point	330.5±0.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₆N₂O₂	Melting Point	36-40 °C(lit.)
MSDS	ChineseUSA	Flash Point	158.4±26.5 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	1-(1,3-benzodioxol-5-ylmethyl)piperazine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	330.5±0.0 °C at 760 mmHg
Melting Point	36-40 °C(lit.)
Molecular Formula	C₁₂H₁₆N₂O₂
Molecular Weight	220.268
Flash Point	158.4±26.5 °C
Exact Mass	220.121185
PSA	33.73000
LogP	1.22
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.577
InChIKey	NBOOZXVYXHATOW-UHFFFAOYSA-N
SMILES	c1cc2c(cc1CN1CCNCC1)OCO2

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM1550000

CHEMICAL NAME :: Piperazine, 1-(3,4-methylenedioxybenzyl)-

CAS REGISTRY NUMBER :: 32231-06-4

BEILSTEIN REFERENCE NO. :: 0885038

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H16-N2-O2

MOLECULAR WEIGHT :: 220.30

WISWESSER LINE NOTATION :: T56 BO DO CHJ G1- DT6M DNTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,555,1974

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S37/39
RIDADR	3259
WGK Germany	3
RTECS	TM1550000
Packaging Group	II
Hazard Class	8
HS Code	2934999090

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles3

Effects of benzylpiperazine derivatives on the neurotoxicity of 3,4-methylenedioxymethamphetamine in rat brain.

Brain Res. 590(1-2) , 341-4, (1992)

The neurotoxicity of 3,4-methylenedioxymethamphetamine (MDMA) in rat brain was attenuated significantly by coadministration of several benzylpiperazines (p-nitrobenzylpiperazine, p-chlorobenzylpiperaz...

A novel caffeic acid-1-piperonylpiperazine hybridization compound HBU-47 inhibits LPS-mediated inflammation in RAW264.7 macrophage cells.

Int. Immunopharmacol. 19(1) , 60-5, (2014)

In the present study, we synthesized a new hybrid compound by coupling caffeic acid and 1-piperonylpiperazine. The synthetic compound, acetyl-caffeic acid-1-piperonylpiperazine (HBU-47), showed potent...

Antagonism of 3,4-methylenedioxymethamphetamine-induced neurotoxicity in rat brain by 1-piperonylpiperazine.

Eur. J. Pharmacol. 228(2-3) , 171-4, (1992)

The effects of 1-piperonylpiperazine and N,alpha-dimethylpiperonylamine, which are weak inhibitors for [3H]5-hydroxytryptamine (5-HT) uptake, on 3,4-methylenedioxymethamphetamine (MDMA)-induced neurot...

Synonyms

1-(1,3-Benzodioxol-5-yl-methyl)piperazine

1-piperonylpiperazine

1-(3,4-Methylenedioxybenzyl)piperazine

EINECS 250-968-5

1-[(3,4-methylenedioxyphenyl)methyl]piperazine

Piperazine,1-(3,4-methylenedioxybenzyl)

1-Benzo[1,3]dioxol-5-ylmethyl-piperazine

4-(3,4-methylenedioxybenzyl)piperazine

5-(piperazinylmethyl)-2H-benzo[d]1,3-dioxolene

1-(1,3-Benzodioxol-5-ylmethyl)piperazine

piperonylpiperazine

1-[(1,3-Benzodioxol-5-yl)methyl]piperazine

MFCD00005834

Methylenedioxybenzylpiperazine

Piperazine, 1-(1,3-benzodioxol-5-ylmethyl)-

1-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazine

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