CAS 10357-84-3|2,6-pyridinediol, hydrochloride

Introduction:Basic information about CAS 10357-84-3|2,6-pyridinediol, hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2,6-pyridinediol, hydrochloride
CAS Number10357-84-3Molecular Weight147.560
Density1.379g/cm3Boiling Point387.2ºC at 760mmHg
Molecular FormulaC5H6ClNO2Melting Point206-208 °C (dec.)(lit.)
MSDSUSAFlash Point188ºC
Symbol
GHS07
Signal WordWarning

Names

Name2,6-Dihydroxypyridine Hydrochloride
SynonymMore Synonyms

Chemical & Physical Properties

Density1.379g/cm3
Boiling Point387.2ºC at 760mmHg
Melting Point206-208 °C (dec.)(lit.)
Molecular FormulaC5H6ClNO2
Molecular Weight147.560
Flash Point188ºC
Exact Mass147.008713
PSA53.35000
LogP1.29480
Vapour Pressure1.35E-07mmHg at 25°C
InChIKeyHNWWAWKDVFVJRG-UHFFFAOYSA-N
SMILESCl.O=c1cccc(O)[nH]1

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk Phrases36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany3
HS Code2933399090

Customs

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles3

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[Estimation of pathways of 5-fluorouracil anabolism in human cancer cells in vitro and in vivo].

Gan To Kagaku Ryoho. 23(6) , 721-31, (1996)

Possible pathways of intracellular phosphorylation of 5-fluorouracil (5-FU) in human cancer cells were investigated in vitro and in vivo. We used two inhibitors which regulate the anabolism of 5-FU fo...

An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans.

J. Bacteriol. 187(24) , 8516-9, (2005)

The enzyme catalyzing the hydrolytic cleavage of 2,6-dihydroxypseudooxynicotine to 2,6-dihydroxypyridine and gamma-N-methylaminobutyrate was found to be encoded on pAO1 of Arthrobacter nicotinovorans....

Combination of the chemotherapeutic agent 5-fluorouracil with an inhibitor of its catabolism results in increased micronucleus induction.

Biochem. Biophys. Res. Commun. 203(2) , 1124-30, (1994)

The rate limiting step in 5-fluorouracil catabolism is catalyzed by the enzyme dihydropyrimidine dehydrogenase. Since degradation of 5-fluorouracil decreases its efficacy in chemotherapy, the inhibiti...

Synonyms

EINECS 233-777-1
6-Hydroxy-2(1H)-pyridinone hydrochloride (1:1)
MFCD00012817
2(1H)-Pyridinone, 6-hydroxy-, hydrochloride (1:1)
Pyridine-2,6-diol hydrochloride (1:1)
2,6-pyridinediol, hydrochloride
6-Hydroxy-2-oxo-1,2-dihydropyridinium chloride
6-hydroxy-1H-pyridin-2-one,hydrochloride
2,6-Pyridinediol Hydrochloride
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