Introduction:Basic information about CAS 3588-17-8|trans,trans-Muconic Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | trans,trans-Muconic Acid |
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| CAS Number | 3588-17-8 | Molecular Weight | 142.109 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 345.4±15.0 °C at 760 mmHg |
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| Molecular Formula | C6H6O4 | Melting Point | 290 °C (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | 176.9±16.9 °C |
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Names
| Name | trans,trans-muconic acid |
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| Synonym | More Synonyms |
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trans,trans-Muconic Acid BiologicalActivity
| Description | trans-trans-Muconic acid is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in humans |
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| Related Catalog | Natural Products >>Acids and AldehydesResearch Areas >>Metabolic Disease |
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| Target | Human Endogenous Metabolite |
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| References | [1]. Bartczak A, ET AL. Evaluation of assays for the identification and quantitation of muconic acid, a benzene metabolite in human urine. J Toxicol Environ Health. 1994 Jul;42(3):245-58. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 345.4±15.0 °C at 760 mmHg |
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| Melting Point | 290 °C (dec.)(lit.) |
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| Molecular Formula | C6H6O4 |
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| Molecular Weight | 142.109 |
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| Flash Point | 176.9±16.9 °C |
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| Exact Mass | 142.026611 |
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| PSA | 74.60000 |
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| LogP | -0.21 |
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| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
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| Index of Refraction | 1.549 |
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| Storage condition | Refrigerator |
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| Water Solubility | insoluble |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- MM2235070
- CHEMICAL NAME :
- 2,4-Hexadienedioic acid, (E,E)-
- CAS REGISTRY NUMBER :
- 3588-17-8
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C6-H6-O4
- MOLECULAR WEIGHT :
- 142.12
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 10 mg/L
- REFERENCE :
- EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 81,77,1989
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Safety Information
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36-S37/39 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | MM2235070 |
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| HS Code | 2917190090 |
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Customs
| HS Code | 2917190090 |
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| Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Articles45
More Articles
| Influence of genetic polymorphism on t,t-MA/S-PMA ratio in 301 benzene exposed subjects. Toxicol. Lett. 231(2) , 205-12, (2014) This study investigated the effect of polymorphic genes GSTT1, GSTM1, GSTA1, EHPX1, NQO1, CYP2E1, CYP1A and MPO on the urinary concentrations and ratio (R) of the benzene metabolites trans,trans-mucon... | |
| Quantitative analysis of catechol and 4-methylcatechol in human urine. Food Chem. Toxicol. 20(5) , 587-90, (1982) A method was developed for the quantitative analysis of catechol and 4-methylcatechol in human urine. [U-14C]Catechol was used as in internal standard. Urine was treated with beta-glucuronidase and su... | |
| Almond consumption reduces oxidative DNA damage and lipid peroxidation in male smokers. J. Nutr. 137(12) , 2717-22, (2007) Smoking increases the risk of several chronic diseases associated with elevated oxidative stress status. Almonds are a good source of antioxidant nutrients and may diminish smoking-related biomarkers ... | |
Synonyms
| (E,E)-muconic acid |
| muconic acid |
| 2,4-HEXADIENEDIOIC ACID, (E,E)- |
| trans,trans muconic acid |
| MFCD00002702 |
| Hexa-2t,4t-diendisaeure |
| EINECS 222-724-8 |
| 2,4-Hexadienedioic acid, (2E,4E)- |
| (E,E)-2,4-hexadienedioic acid |
| 2,4-hexadienedioic acid |
| trans,trans-Muconic acid |
| MUCONIC ACID,TRANS,TRANS |
| Trans-Muconic Acid |
| (2E,4E)-hexa-2,4-dienedioic acid |
| 2,4-HEXADIENE-1,6-DIOIC ACID |
| t,t-Muconic acid |
| (E,E)-2,4-Hexadienedioate |
| hexa-2t,4t-dienedioic acid |
| hexa-2,4-dienedioic acid |
| (2E,4E)-2,4-Hexadienedioic acid |
| trans,trans-2,4-Hexadienedioic Acid |